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High-throughput small molecule screen identifies inhibitors of microsporidia invasion and proliferation in C. elegans

Microsporidia are a diverse group of fungal-related obligate intracellular parasites that infect most animal phyla. Despite the emerging threat that microsporidia represent to humans and agricultural animals, few reliable treatment options exist. Here, we develop a high-throughput screening method f...

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Detalles Bibliográficos
Autores principales: Murareanu, Brandon M., Antao, Noelle V., Zhao, Winnie, Dubuffet, Aurore, El Alaoui, Hicham, Knox, Jessica, Ekiert, Damian C., Bhabha, Gira, Roy, Peter J., Reinke, Aaron W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9513054/
https://www.ncbi.nlm.nih.gov/pubmed/36163337
http://dx.doi.org/10.1038/s41467-022-33400-y

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