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The genesis and evolution of acute myeloid leukemia stem cells in the microenvironment: From biology to therapeutic targeting

Acute myeloid leukemia (AML) is a hematological malignancy characterized by cytogenetic and genomic alterations. Up to now, combination chemotherapy remains the standard treatment for leukemia. However, many individuals diagnosed with AML develop chemotherapeutic resistance and relapse. Recently, it...

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Detalles Bibliográficos
Autores principales: Chen, Yongfeng, Li, Jing, Xu, Linglong, Găman, Mihnea-Alexandru, Zou, Zhenyou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9513079/
https://www.ncbi.nlm.nih.gov/pubmed/36163119
http://dx.doi.org/10.1038/s41420-022-01193-0