Cargando…

Novel macrophage-related gene prognostic index for glioblastoma associated with M2 macrophages and T cell dysfunction

This study aims to construct a Macrophage-Related Gene Prognostic Index (MRGPI) for glioblastoma (GBM) and explore the underlying molecular, metabolic, and immunological features. Based on the GBM dataset from The Cancer Genome Atlas (n = 156), 13 macrophage-related hub genes were identified by weig...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ji, Hang, Liu, Zhihui, Wang, Fang, Sun, Haogeng, Wang, Nan, Liu, Yi, Hu, Shaoshan, You, Chao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9513135/ https://www.ncbi.nlm.nih.gov/pubmed/36177003 http://dx.doi.org/10.3389/fimmu.2022.941556

Ejemplares similares

Integrated genomic, transcriptomic, and epigenetic analyses identify a leukotriene synthesis-related M2 macrophage gene signature that predicts prognosis and treatment vulnerability in gliomas
por: Ji, Hang, et al.
Publicado: (2022)

COVPRIG robustly predicts the overall survival of IDH wild-type glioblastoma and highlights METTL1(+) neural-progenitor-like tumor cell in driving unfavorable outcome
por: Ji, Hang, et al.
Publicado: (2023)

Construction of Interferon-Gamma-Related Gene Signature to Characterize the Immune-Inflamed Phenotype of Glioblastoma and Predict Prognosis, Efficacy of Immunotherapy and Radiotherapy
por: Ji, Hang, et al.
Publicado: (2021)

M1 Macrophage-Derived Nanovesicles Repolarize M2 Macrophages for Inhibiting the Development of Endometriosis
por: Li, Qiuju, et al.
Publicado: (2021)

Recognition of Tumor-Associated Antigens and Immune Subtypes in Glioma for mRNA Vaccine Development
por: Ma, Shuai, et al.
Publicado: (2021)

Metformin, Macrophage Dysfunction and Atherosclerosis
por: Feng, Xiaojun, et al.
Publicado: (2021)

Molecular Mechanisms That Influence the Macrophage M1–M2 Polarization Balance
por: Wang, Nan, et al.
Publicado: (2014)

Prognostic and immunological significance of an M1 macrophage-related gene signature in osteosarcoma
por: Mao, Xiaoyu, et al.
Publicado: (2023)

Coagulation Factor X Regulated by CASC2c Recruited Macrophages and Induced M2 Polarization in Glioblastoma Multiforme
por: Zhang, Yan, et al.
Publicado: (2018)

Glioma-associated microglia/macrophages (GAMs) in glioblastoma: Immune function in the tumor microenvironment and implications for immunotherapy
por: Lin, Chao, et al.
Publicado: (2023)

PD-L1-Mediated Immunosuppression in Glioblastoma Is Associated With the Infiltration and M2-Polarization of Tumor-Associated Macrophages
por: Zhu, Zhiyuan, et al.
Publicado: (2020)

Identification of CD101 in Glioma: A Novel Prognostic Indicator Expressed on M2 Macrophages
por: Liu, Yuyang, et al.
Publicado: (2022)

The diversity and dynamics of tumor-associated macrophages in recurrent glioblastoma
por: Zhang, Lingyun, et al.
Publicado: (2023)

Corrigendum: Coagulation Factor X Regulated by CASC2c Recruited Macrophages and Induced M2 Polarization in Glioblastoma Multiforme
por: Zhang, Yan, et al.
Publicado: (2020)

Mapping the Tumor Microenvironment in TNBC and Deep Exploration for M1 Macrophages-Associated Prognostic Genes
por: Xu, Baojin, et al.
Publicado: (2022)

Programmed Cell Death 10 Mediated CXCL2-CXCR2 Signaling in Regulating Tumor-Associated Microglia/Macrophages Recruitment in Glioblastoma
por: Zhang, Quan, et al.
Publicado: (2021)

Tumor-associated microglia and macrophages in glioblastoma: From basic insights to therapeutic opportunities
por: Wang, Guoqing, et al.
Publicado: (2022)

Targeting tumor-associated macrophages for the immunotherapy of glioblastoma: Navigating the clinical and translational landscape
por: Wang, Zide, et al.
Publicado: (2022)

Dysfunction of macrophages leads to diabetic bone regeneration deficiency
por: Shen, Yufeng, et al.
Publicado: (2022)

Much More than M1 and M2 Macrophages, There are also CD169(+) and TCR(+) Macrophages
por: Chávez-Galán, Leslie, et al.
Publicado: (2015)

Multiomics Data Analysis and Identification of Immune-Related Prognostic Signatures With Potential Implications in Prognosis and Immune Checkpoint Blockade Therapy of Glioblastoma
por: Ma, Shuai, et al.
Publicado: (2022)

Macrophage autophagy in macrophage polarization, chronic inflammation and organ fibrosis
por: Wen, Jun-Hao, et al.
Publicado: (2022)

Cardiac resident macrophages: key regulatory mediators in the aftermath of myocardial infarction
por: Chen, Cong, et al.
Publicado: (2023)

Alpha fetoprotein promotes polarization of macrophages towards M2-like phenotype and inhibits macrophages to phagocytize hepatoma cells
por: Zhang, Minni, et al.
Publicado: (2023)

Model for predicting immunotherapy based on M2 macrophage infiltration in TNBC
por: Wu, Haoming, et al.
Publicado: (2023)

Malignant Evaluation and Clinical Prognostic Values of m6A RNA Methylation Regulators in Glioblastoma
por: Du, Jianyang, et al.
Publicado: (2020)

5-Methylcytosine Related LncRNAs Reveal Immune Characteristics, Predict Prognosis and Oncology Treatment Outcome in Lower-Grade Gliomas
por: Zhang, Jiheng, et al.
Publicado: (2022)

TP53I13 promotes metastasis in glioma via macrophages, neutrophils, and fibroblasts and is a potential prognostic biomarker
por: Ge, Xinqi, et al.
Publicado: (2022)

Modulators of the Balance between M1 and M2 Macrophages during Pregnancy
por: Zhang, Yong-Hong, et al.
Publicado: (2017)

IFIH1 Contributes to M1 Macrophage Polarization in ARDS
por: Zhang, Shi, et al.
Publicado: (2021)

Crosstalk Between Tumor-Associated Microglia/Macrophages and CD8-Positive T Cells Plays a Key Role in Glioblastoma
por: Tu, Sheng, et al.
Publicado: (2021)

Anatomy of a Discovery: M1 and M2 Macrophages
por: Mills, Charles Dudley
Publicado: (2015)

Ontogeny of Synovial Macrophages and the Roles of Synovial Macrophages From Different Origins in Arthritis
por: Tu, Jiajie, et al.
Publicado: (2019)

Changes in the Small Noncoding RNAome During M1 and M2 Macrophage Polarization
por: Ma, Ding, et al.
Publicado: (2022)

Identification of a six-gene prognostic signature for bladder cancer associated macrophage
por: Jiang, Yunzhong, et al.
Publicado: (2022)

JEV Infection Induces M-MDSC Differentiation Into CD3(+) Macrophages in the Brain
por: Zhang, Nan, et al.
Publicado: (2022)

Macrophage Polarization: Different Gene Signatures in M1(LPS+) vs. Classically and M2(LPS–) vs. Alternatively Activated Macrophages
por: Orecchioni, Marco, et al.
Publicado: (2019)

Metabolic-related gene pairs signature analysis identifies ABCA1 expression levels on tumor-associated macrophages as a prognostic biomarker in primary IDH(WT) glioblastoma
por: Wang, Shiqun, et al.
Publicado: (2022)

Novel Immune-Related Gene-Based Signature Characterizing an Inflamed Microenvironment Predicts Prognosis and Radiotherapy Efficacy in Glioblastoma
por: Ji, Hang, et al.
Publicado: (2022)

M1/M2 Macrophage Polarity in Normal and Complicated Pregnancy
por: Brown, Mary B., et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_gs435fbb76heo6hptohlnip0lq