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DNA damage response and GATA4 signaling in cellular senescence and aging-related pathology

Aging is the continuous degradation of biological function and structure with time, and cellular senescence lies at its core. DNA damage response (DDR) can activate Ataxia telangiectasia-mutated serine/threonine kinase (ATM) and Rad3-related serine/threonine kinase (ATR), after which p53 activates p...

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Detalles Bibliográficos
Autores principales:	Xiong, Hao, Hua, Fuzhou, Dong, Yao, Lin, Yue, Ying, Jun, Liu, Jie, Wang, Xifeng, Zhang, Lieliang, Zhang, Jing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Aging Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9513149/ https://www.ncbi.nlm.nih.gov/pubmed/36177479 http://dx.doi.org/10.3389/fnagi.2022.933015

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