Involvement of TLR2–TLR4, NLRP3, and IL-17 in pain induced by a novel Sprague-Dawley rat model of experimental autoimmune encephalomyelitis

Up to 92% of patients suffering from multiple sclerosis (MS) experience pain, most without adequate treatment, and many report pain long before motor symptoms associated with MS diagnosis. In the most commonly studied rodent model of MS, experimental autoimmune encephalomyelitis (EAE), motor impairm...

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Detalles Bibliográficos
Autores principales: Kwilasz, Andrew J., Clements, Madison A., Larson, Tracey A., Harris, Kevin M., Litwiler, Scott T., Woodall, Brodie J., Todd, Laurel S., Schrama, Anouk E. W., Mitten, Eric H., Maier, Steven F., Van Dam, Anne-Marie, Rice, Kenner C., Watkins, Linda R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pain Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9513159/
https://www.ncbi.nlm.nih.gov/pubmed/36176709
http://dx.doi.org/10.3389/fpain.2022.932530

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