Inhibition of Plasmodium falciparum Hsp70-Hop partnership by 2-phenylthynesulfonamide

Plasmodium falciparum Hsp70-1 (PfHsp70-1; PF3D7_0818900) and PfHsp90 (PF3D7_0708400) are essential cytosol localized chaperones of the malaria parasite. The two chaperones form a functional complex via the adaptor protein, Hsp90-Hsp70 organizing protein (PfHop [PF3D7_1434300]), which modulates the i...

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Detalles Bibliográficos
Autores principales: Muthelo, Tshifhiwa, Mulaudzi, Vhahangwele, Netshishivhe, Munei, Dongola, Tendamudzimu Harmfree, Kok, Michelle, Makumire, Stanley, de Villiers, Marianne, Burger, Adélle, Zininga, Tawanda, Shonhai, Addmore
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9513230/
https://www.ncbi.nlm.nih.gov/pubmed/36177352
http://dx.doi.org/10.3389/fmolb.2022.947203

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9513230/
https://www.ncbi.nlm.nih.gov/pubmed/36177352
http://dx.doi.org/10.3389/fmolb.2022.947203

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