Pro-metastatic and mesenchymal gene expression signatures characterize circulating tumor cells of neuroblastoma patients with bone marrow metastases and relapse

Existing marker-based methods of minimal residual disease (MRD) determination in neuroblastoma do not effectively enrich for the circulating disease cell population. Given the relative size differential of neuroblastoma tumor cells over normal hematogenous cells, we hypothesized that cell size-based...

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Detalles Bibliográficos
Autores principales: Loh, Amos H. P., Angelina, Clara, Wong, Meng Kang, Tan, Sheng Hui, Sukhatme, Sarvesh A., Yeo, Trifanny, Lim, Su Bin, Lee, York Tien, Soh, Shui Yen, Leung, Wing, Chang, Kenneth T. E., Chua, Yong Wei, Alkaff, Syed M. F., Lim, Tony K. H., Lim, Chwee Teck, Chen, Zhi Xiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9513238/
https://www.ncbi.nlm.nih.gov/pubmed/36176417
http://dx.doi.org/10.3389/fonc.2022.939460

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