Brønsted acid catalyzed remote C6 functionalization of 2,3-disubstituted indoles with β,γ-unsaturated α-ketoester

A metal-free catalytic approach for the remote C6-functionalization of 2,3-disubstituted indoles has been developed. In the presence of catalytic amounts of Brønsted acid, the β,γ-unsaturated α-ketoesters react with 2,3-disubstituted indoles at the C6 position selectively. Under mild reaction condit...

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Detalles Bibliográficos
Autores principales: Zhang, You-Ya, Li, Lin, Zhang, Xiang-Zhi, Peng, Jin-Bao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9513241/
https://www.ncbi.nlm.nih.gov/pubmed/36176896
http://dx.doi.org/10.3389/fchem.2022.992398

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9513241/
https://www.ncbi.nlm.nih.gov/pubmed/36176896
http://dx.doi.org/10.3389/fchem.2022.992398

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