cGAS-STING activation contributes to podocyte injury in diabetic kidney disease

Diabetic kidney disease (DKD) is the leading cause of end-stage renal diseases. DKD does not have efficacious treatment. The cGAS-STING pathway is activated in podocytes at the early stage of kidney dysfunction, which is associated with the activation of STING downstream effectors TBK1 and NF-κB but...

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Detalles Bibliográficos
Autores principales: Zang, Nan, Cui, Chen, Guo, Xinghong, Song, Jia, Hu, Huiqing, Yang, Mengmeng, Xu, Mingyue, Wang, Lingshu, Hou, Xinguo, He, Qin, Sun, Zheng, Wang, Chuan, Chen, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9513272/
https://www.ncbi.nlm.nih.gov/pubmed/36176590
http://dx.doi.org/10.1016/j.isci.2022.105145

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