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ATP-binding cassette protein ABCA7 deficiency impairs sphingomyelin synthesis, cognitive discrimination, and synaptic plasticity in the entorhinal cortex

Sphingomyelin (SM) is an abundant plasma membrane and plasma lipoprotein sphingolipid. We previously reported that ATP-binding cassette family A protein 1 (ABCA1) deficiency in humans and mice decreases plasma SM levels. However, overexpression, induction, downregulation, inhibition, and knockdown o...

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Detalles Bibliográficos
Autores principales:	Iqbal, Jahangir, Suarez, Manuel D., Yadav, Pradeep K., Walsh, Meghan T., Li, Yimeng, Wu, Yiyang, Huang, Zhengwei, James, Antonisamy William, Escobar, Victor, Mokbe, Ashwag, Brickman, Adam M., Luchsinger, José A., Dai, Kezhi, Moreno, Herman, Hussain, M. Mahmood
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9513280/ https://www.ncbi.nlm.nih.gov/pubmed/36007616 http://dx.doi.org/10.1016/j.jbc.2022.102411

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