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Favorable outcome of high-dose chemotherapy and autologous hematopoietic stem cell transplantation in patients with nonmetastatic osteosarcoma and low-degree necrosis

BACKGROUND: A low-degree tumor necrosis after neoadjuvant chemotherapy is a poor prognostic factor for osteosarcoma (OSA). However, the role of high-dose chemotherapy (HDC) and autologous hematopoietic stem cell transplantation in OSA remains controversial. We analyzed the treatment outcomes and pro...

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Detalles Bibliográficos
Autores principales: Hong, Kyung Taek, Park, Hyun Jin, Kim, Bo Kyung, An, Hong Yul, Choi, Jung Yoon, Cheon, Jung-Eun, Park, Sung-Hye, Kim, Han-Soo, Kang, Hyoung Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9513349/
https://www.ncbi.nlm.nih.gov/pubmed/36176408
http://dx.doi.org/10.3389/fonc.2022.978949