Cargando…

Effect of taurine in muscle damage markers and inflammatory cytokines in running exercise

This study aimed to investigate the effect of taurine on muscle damage markers and inflammatory markers in the running. For that, ten healthy volunteers participated in this study (mean ± SEM; age 24 ± 1 year, body mass 72.2 ± 4.89 kg, height 174.03 ± 2.85 cm, and BMI 23.83 ± 1.27). The running exer...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Yucong, Xu, Tao, Zhao, Hui, Gu, Chunxiao, Li, Zhongzheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9513359/
https://www.ncbi.nlm.nih.gov/pubmed/36176774
http://dx.doi.org/10.3389/fphys.2022.1008060
_version_ 1784798044409036800
author Wang, Yucong
Xu, Tao
Zhao, Hui
Gu, Chunxiao
Li, Zhongzheng
author_facet Wang, Yucong
Xu, Tao
Zhao, Hui
Gu, Chunxiao
Li, Zhongzheng
author_sort Wang, Yucong
collection PubMed
description This study aimed to investigate the effect of taurine on muscle damage markers and inflammatory markers in the running. For that, ten healthy volunteers participated in this study (mean ± SEM; age 24 ± 1 year, body mass 72.2 ± 4.89 kg, height 174.03 ± 2.85 cm, and BMI 23.83 ± 1.27). The running exercise was performed for 5 km, and blood was taken pre-exercise and pre-exercise + tau and post-exercise and post-exercise + tau for biochemical assessment. We assessed serum creatine kinase (CK), CK isoenzyme, Lactate dehydrogenase (LDH), aspartate transaminase (AST), tumor necrosis factor-alpha (TNF-alpha), and interleukin-6 (IL-6). CK level was not significantly different in the control and taurine (tau) administrated groups. However, creatine kinase isoenzyme was decreased in the pre-exercise + tau group when compared to the post-exercise + tau group. AST level was increased significantly in the post-exercise compared to the post-exercise + tau group. There was no significant difference observed in the LDH level in both post-exercise and post-exercise + tau. TNF-alpha level was not also significantly different in both post-exercise and post-exercise + tau. However, IL-6 was decreased in the post-exercise + tau when compared to the post-exercise group. In conclusion, we observed that taurine decreases the inflammatory response by decreasing IL-6 and AST, suggesting the role of taurine in regulating inflammatory response could help to increase running performance.
format Online
Article
Text
id pubmed-9513359
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher Frontiers Media S.A.
record_format MEDLINE/PubMed
spelling pubmed-95133592022-09-28 Effect of taurine in muscle damage markers and inflammatory cytokines in running exercise Wang, Yucong Xu, Tao Zhao, Hui Gu, Chunxiao Li, Zhongzheng Front Physiol Physiology This study aimed to investigate the effect of taurine on muscle damage markers and inflammatory markers in the running. For that, ten healthy volunteers participated in this study (mean ± SEM; age 24 ± 1 year, body mass 72.2 ± 4.89 kg, height 174.03 ± 2.85 cm, and BMI 23.83 ± 1.27). The running exercise was performed for 5 km, and blood was taken pre-exercise and pre-exercise + tau and post-exercise and post-exercise + tau for biochemical assessment. We assessed serum creatine kinase (CK), CK isoenzyme, Lactate dehydrogenase (LDH), aspartate transaminase (AST), tumor necrosis factor-alpha (TNF-alpha), and interleukin-6 (IL-6). CK level was not significantly different in the control and taurine (tau) administrated groups. However, creatine kinase isoenzyme was decreased in the pre-exercise + tau group when compared to the post-exercise + tau group. AST level was increased significantly in the post-exercise compared to the post-exercise + tau group. There was no significant difference observed in the LDH level in both post-exercise and post-exercise + tau. TNF-alpha level was not also significantly different in both post-exercise and post-exercise + tau. However, IL-6 was decreased in the post-exercise + tau when compared to the post-exercise group. In conclusion, we observed that taurine decreases the inflammatory response by decreasing IL-6 and AST, suggesting the role of taurine in regulating inflammatory response could help to increase running performance. Frontiers Media S.A. 2022-09-13 /pmc/articles/PMC9513359/ /pubmed/36176774 http://dx.doi.org/10.3389/fphys.2022.1008060 Text en Copyright © 2022 Wang, Xu, Zhao, Gu and Li. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Physiology
Wang, Yucong
Xu, Tao
Zhao, Hui
Gu, Chunxiao
Li, Zhongzheng
Effect of taurine in muscle damage markers and inflammatory cytokines in running exercise
title Effect of taurine in muscle damage markers and inflammatory cytokines in running exercise
title_full Effect of taurine in muscle damage markers and inflammatory cytokines in running exercise
title_fullStr Effect of taurine in muscle damage markers and inflammatory cytokines in running exercise
title_full_unstemmed Effect of taurine in muscle damage markers and inflammatory cytokines in running exercise
title_short Effect of taurine in muscle damage markers and inflammatory cytokines in running exercise
title_sort effect of taurine in muscle damage markers and inflammatory cytokines in running exercise
topic Physiology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9513359/
https://www.ncbi.nlm.nih.gov/pubmed/36176774
http://dx.doi.org/10.3389/fphys.2022.1008060
work_keys_str_mv AT wangyucong effectoftaurineinmuscledamagemarkersandinflammatorycytokinesinrunningexercise
AT xutao effectoftaurineinmuscledamagemarkersandinflammatorycytokinesinrunningexercise
AT zhaohui effectoftaurineinmuscledamagemarkersandinflammatorycytokinesinrunningexercise
AT guchunxiao effectoftaurineinmuscledamagemarkersandinflammatorycytokinesinrunningexercise
AT lizhongzheng effectoftaurineinmuscledamagemarkersandinflammatorycytokinesinrunningexercise