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Engineering constructed of high selectivity dexamethasone aptamer based on truncation and mutation technology

Various biosensors based on aptamers are currently the most popular rapid detection approaches, but the performance of these sensors is closely related to the affinity of aptamers. In this work, a strategy for constructed high-affinity aptamer was proposed. By truncating the bases flanking the 59 nt...

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Detalles Bibliográficos
Autores principales: Qin, Yadi, Qin, Yanan, Bubiajiaer, Hayilati, Chen, Fengxia, Yao, Jun, Zhang, Minwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9513367/
https://www.ncbi.nlm.nih.gov/pubmed/36177181
http://dx.doi.org/10.3389/fbioe.2022.994711

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