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SARS-CoV-2 Nsp14 protein associates with IMPDH2 and activates NF-κB signaling

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection leads to NF-κB activation and induction of pro-inflammatory cytokines, though the underlying mechanism for this activation is not fully understood. Our results reveal that the SARS-CoV-2 Nsp14 protein contributes to the viral act...

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Detalles Bibliográficos
Autores principales:	Li, Tai-Wei, Kenney, Adam D., Park, Jun-Gyu, Fiches, Guillaume N., Liu, Helu, Zhou, Dawei, Biswas, Ayan, Zhao, Weiqiang, Que, Jianwen, Santoso, Netty, Martinez-Sobrido, Luis, Yount, Jacob S., Zhu, Jian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9513374/ https://www.ncbi.nlm.nih.gov/pubmed/36177032 http://dx.doi.org/10.3389/fimmu.2022.1007089

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