Critical involvement of lysyl oxidase in seizure-induced neuronal damage through ERK-Alox5-dependent ferroptosis and its therapeutic implications

Recent insights collectively suggest the important roles of lysyl oxidase (LysOX) in the pathological processes of several acute and chronic neurological diseases, but the molecular regulatory mechanisms remain elusive. Herein, we explore the regulatory role of LysOX in the seizure-induced ferroptot...

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Detalles Bibliográficos
Autores principales: Mao, Xiaoyuan, Wang, Xuan, Jin, Mingzhu, Li, Qin, Jia, Jining, Li, Menghuan, Zhou, Honghao, Liu, Zhaoqian, Jin, Weilin, Zhao, Yanli, Luo, Zhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9513491/
https://www.ncbi.nlm.nih.gov/pubmed/36176900
http://dx.doi.org/10.1016/j.apsb.2022.04.017

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