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Reprogramming alternative macrophage polarization by GATM-mediated endogenous creatine synthesis: A potential target for HDM-induced asthma treatment
Cellular energy metabolism plays a crucial role in the regulation of macrophage polarization and in the execution of immune functions. A recent study showed that Slc6a8-mediated creatine uptake from exogenous supplementation modulates macrophage polarization, yet little is known about the role of th...
Autores principales: | Yu, Li, Wang, Lingwei, Hu, Guang, Ren, Laibin, Qiu, Chen, Li, Shun, Zhou, Xiaohui, Chen, Shanze, Chen, Rongchang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9513582/ https://www.ncbi.nlm.nih.gov/pubmed/36177049 http://dx.doi.org/10.3389/fimmu.2022.937331 |
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