Cargando…
Analgesic effect of recombinant GABAergic precursors releasing ω-conotoxin MVIIA in a model of peripheral nerve injury in rats
Development of chronic pain has been attributed to dysfunctional GABA signaling in the spinal cord. Direct pharmacological interventions on GABA signaling are usually not very efficient and often accompanied by side effects due to the widespread distribution of GABA receptors in CNS. Transplantation...
Autores principales: | Jergova, Stanislava, Hernandez, Melissa, Sagen, Jacqueline |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9513588/ https://www.ncbi.nlm.nih.gov/pubmed/36113096 http://dx.doi.org/10.1177/17448069221129829 |
Ejemplares similares
-
ω-Conotoxins GVIA, MVIIA and CVID: SAR and Clinical Potential
por: Schroeder, Christina I., et al.
Publicado: (2006) -
TAT-Modified ω-Conotoxin MVIIA for Crossing the Blood-Brain Barrier
por: Yu, Shuo, et al.
Publicado: (2019) -
Attenuation of SCI-Induced Hypersensitivity by Intensive Locomotor Training and Recombinant GABAergic Cells
por: Jergova, Stanislava, et al.
Publicado: (2023) -
Self-Assembly Nanostructure of Myristoylated ω-Conotoxin MVIIA Increases the Duration of Efficacy and Reduces Side Effects
por: Ding, Xiufang, et al.
Publicado: (2023) -
Predifferentiated GABAergic Neural Precursor Transplants for Alleviation of Dysesthetic Central Pain Following Excitotoxic Spinal Cord Injury
por: Lee, Jeung Woon, et al.
Publicado: (2012)