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Adverse effects of Lugol’s iodine: Heart failure in a patient with subcutaneous phycomycosis from a resource-limited setting

Subcutaneous phycomycosis becomes a chronic, debilitating condition if left untreated. Treatment includes oral antifungal therapy, though oral potassium iodide has been used in resource-limited settings. Lugol's iodine has been an effective substitute, but little is known about its safety. We r...

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Autores principales: Karahalios, Dean S., Shaw, Andrea, Arunga, Bonnke, Lenehan, Carlee, Sing'oei, Valentine, Otieno, Walter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9513598/
https://www.ncbi.nlm.nih.gov/pubmed/36176458
http://dx.doi.org/10.1016/j.mmcr.2022.09.001
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author Karahalios, Dean S.
Shaw, Andrea
Arunga, Bonnke
Lenehan, Carlee
Sing'oei, Valentine
Otieno, Walter
author_facet Karahalios, Dean S.
Shaw, Andrea
Arunga, Bonnke
Lenehan, Carlee
Sing'oei, Valentine
Otieno, Walter
author_sort Karahalios, Dean S.
collection PubMed
description Subcutaneous phycomycosis becomes a chronic, debilitating condition if left untreated. Treatment includes oral antifungal therapy, though oral potassium iodide has been used in resource-limited settings. Lugol's iodine has been an effective substitute, but little is known about its safety. We report a case of subcutaneous phycomycosis complicated by heart failure during treatment with Lugol's iodine. We review subcutaneous phycomycosis, iodine-mediated cardiotoxicity, as well as social determinants of health relevant to our case, suggesting that Lugol's iodine may only be an effective treatment with proper dosing and long-term monitoring.
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spelling pubmed-95135982022-09-28 Adverse effects of Lugol’s iodine: Heart failure in a patient with subcutaneous phycomycosis from a resource-limited setting Karahalios, Dean S. Shaw, Andrea Arunga, Bonnke Lenehan, Carlee Sing'oei, Valentine Otieno, Walter Med Mycol Case Rep Case Report Subcutaneous phycomycosis becomes a chronic, debilitating condition if left untreated. Treatment includes oral antifungal therapy, though oral potassium iodide has been used in resource-limited settings. Lugol's iodine has been an effective substitute, but little is known about its safety. We report a case of subcutaneous phycomycosis complicated by heart failure during treatment with Lugol's iodine. We review subcutaneous phycomycosis, iodine-mediated cardiotoxicity, as well as social determinants of health relevant to our case, suggesting that Lugol's iodine may only be an effective treatment with proper dosing and long-term monitoring. Elsevier 2022-09-16 /pmc/articles/PMC9513598/ /pubmed/36176458 http://dx.doi.org/10.1016/j.mmcr.2022.09.001 Text en © 2022 The Authors https://creativecommons.org/licenses/by/4.0/This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Case Report
Karahalios, Dean S.
Shaw, Andrea
Arunga, Bonnke
Lenehan, Carlee
Sing'oei, Valentine
Otieno, Walter
Adverse effects of Lugol’s iodine: Heart failure in a patient with subcutaneous phycomycosis from a resource-limited setting
title Adverse effects of Lugol’s iodine: Heart failure in a patient with subcutaneous phycomycosis from a resource-limited setting
title_full Adverse effects of Lugol’s iodine: Heart failure in a patient with subcutaneous phycomycosis from a resource-limited setting
title_fullStr Adverse effects of Lugol’s iodine: Heart failure in a patient with subcutaneous phycomycosis from a resource-limited setting
title_full_unstemmed Adverse effects of Lugol’s iodine: Heart failure in a patient with subcutaneous phycomycosis from a resource-limited setting
title_short Adverse effects of Lugol’s iodine: Heart failure in a patient with subcutaneous phycomycosis from a resource-limited setting
title_sort adverse effects of lugol’s iodine: heart failure in a patient with subcutaneous phycomycosis from a resource-limited setting
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9513598/
https://www.ncbi.nlm.nih.gov/pubmed/36176458
http://dx.doi.org/10.1016/j.mmcr.2022.09.001
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