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A platinum@polymer-catechol nanobraker enables radio-immunotherapy for crippling melanoma tumorigenesis, angiogenesis, and radioresistance

Malignant melanoma cell-intrinsic PD-1:PD-L1 interaction thrusts tumorigenesis, angiogenesis, and radioresistance via mTOR hyperactivation to aggravate circumjacent aggression. Interdicting melanoma intrinsic growth signals, including the blockade of PD-L1 and mTOR signaling concurrently, cooperativ...

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Detalles Bibliográficos
Autores principales: Li, Wenxi, Yan, Jie, Tian, Hao, Li, Bei, Wang, Guohao, Sang, Wei, Zhang, Zhan, Zhang, Xuanjun, Dai, Yunlu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: KeAi Publishing 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9513621/
https://www.ncbi.nlm.nih.gov/pubmed/36203954
http://dx.doi.org/10.1016/j.bioactmat.2022.09.006