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Genetic signature of differentiated thyroid carcinoma susceptibility: a machine learning approach

To identify a peculiar genetic combination predisposing to differentiated thyroid carcinoma (DTC), we selected a set of single nucleotide polymorphisms (SNPs) associated with DTC risk, considering polygenic risk score (PRS), Bayesian statistics and a machine learning (ML) classifier to describe case...

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Detalles Bibliográficos
Autores principales: Brigante, Giulia, Lazzaretti, Clara, Paradiso, Elia, Nuzzo, Federico, Sitti, Martina, Tüttelmann, Frank, Moretti, Gabriele, Silvestri, Roberto, Gemignani, Federica, Försti, Asta, Hemminki, Kari, Elisei, Rossella, Romei, Cristina, Zizzi, Eric Adriano, Deriu, Marco Agostino, Simoni, Manuela, Landi, Stefano, Casarini, Livio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bioscientifica Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9513665/
https://www.ncbi.nlm.nih.gov/pubmed/35976137
http://dx.doi.org/10.1530/ETJ-22-0058