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Efficacy and safety of glibenclamide therapy after intracerebral haemorrhage (GATE-ICH): A multicentre, prospective, randomised, controlled, open-label, blinded-endpoint, phase 2 clinical trial
BACKGROUND: Glibenclamide is a promising agent for treating brain oedema, but whether it improves clinical outcomes in patients with intracerebral haemorrhage (ICH) remains unclear. In this study, we aimed to explore the efficacy and safety of glibenclamide treatment in patients with acute ICH. METH...
Autores principales: | Zhao, Jingjing, Song, Changgeng, Li, Deshuai, Yang, Xiai, Yu, Liping, Wang, Kangjun, Wu, Jun, Wang, Xiaofeng, Li, Dongsong, Zhang, Bo, Li, Binyong, Guo, Jun, Feng, Weikui, Fu, Feng, Gu, Xinrong, Qian, Jian, Li, Jialong, Yuan, Xiangjun, Liu, Qiuwu, Chen, Jiang, Wang, Xiaocheng, Liu, Yi, Wei, Dong, Wang, Ling, Shang, Lei, Yang, Fang, Jiang, Wen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9513728/ https://www.ncbi.nlm.nih.gov/pubmed/36177443 http://dx.doi.org/10.1016/j.eclinm.2022.101666 |
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