The RNA-binding protein AUF1 facilitates Akt phosphorylation at the membrane

Mammalian target of rapamycin (mTOR), which is part of mTOR complex 1 (mTORC1) and mTORC2, controls cellular metabolism in response to levels of nutrients and other growth signals. A hallmark of mTORC2 activation is the phosphorylation of Akt, which becomes upregulated in cancer. How mTORC2 modulate...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Mei-Ling, Ragupathi, Aparna, Patel, Nikhil, Hernandez, Tatiana, Magsino, Jedrick, Werlen, Guy, Brewer, Gary, Jacinto, Estela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9513781/
https://www.ncbi.nlm.nih.gov/pubmed/36041631
http://dx.doi.org/10.1016/j.jbc.2022.102437

Ejemplares similares

Ejemplares similares