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Protein arginine methyltransferase 5 is essential for oncogene product EWSR1-ATF1-mediated gene transcription in clear cell sarcoma

Transcription dysregulation is common in sarcomas driven by oncogenic transcription factors. Clear cell sarcoma of soft tissue (CCSST) is a rare sarcoma with poor prognosis presently with no therapy. It is characterized by a balanced t(12;22) (q13;q12) chromosomal translocation, resulting in a fusio...

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Detalles Bibliográficos
Autores principales:	Li, Bingbing X., David, Larry L., Davis, Lara E., Xiao, Xiangshu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9513783/ https://www.ncbi.nlm.nih.gov/pubmed/36041632 http://dx.doi.org/10.1016/j.jbc.2022.102434

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