Single-cell analysis reveals heterogeneity of juvenile idiopathic arthritis fibroblast-like synoviocytes with implications for disease subtype

BACKGROUND: Fibroblast-like synoviocytes (FLS) play a crucial role in JIA pathogenesis; however, the mechanisms by which they contribute to disease progression are not well described. Previous studies demonstrated that rheumatoid arthritis FLS are heterogeneous, and subpopulations with transformed,...

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Detalles Bibliográficos
Autores principales: Simonds, Megan M., Sullivan, Kathleen E., Brescia, AnneMarie C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9513865/
https://www.ncbi.nlm.nih.gov/pubmed/36167601
http://dx.doi.org/10.1186/s13075-022-02913-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9513865/
https://www.ncbi.nlm.nih.gov/pubmed/36167601
http://dx.doi.org/10.1186/s13075-022-02913-8

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