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Single-cell analysis reveals heterogeneity of juvenile idiopathic arthritis fibroblast-like synoviocytes with implications for disease subtype
BACKGROUND: Fibroblast-like synoviocytes (FLS) play a crucial role in JIA pathogenesis; however, the mechanisms by which they contribute to disease progression are not well described. Previous studies demonstrated that rheumatoid arthritis FLS are heterogeneous, and subpopulations with transformed,...
Autores principales: | Simonds, Megan M., Sullivan, Kathleen E., Brescia, AnneMarie C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9513865/ https://www.ncbi.nlm.nih.gov/pubmed/36167601 http://dx.doi.org/10.1186/s13075-022-02913-8 |
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