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Integrated genomic analysis reveals actionable targets in pediatric spinal cord low-grade gliomas

Gliomas are the most common central nervous tumors in children and adolescents. However, spinal cord low-grade gliomas (sLGGs) are rare, with scarce information on tumor genomics and epigenomics. To define the molecular landscape of sLGGs, we integrated clinical data, histology, and multi-level gene...

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Detalles Bibliográficos
Autores principales: Adela, Misove, Ales, Vicha, Petr, Broz, Katerina, Vanova, David, Sumerauer, Lucie, Stolova, Lucie, Sramkova, Miroslav, Koblizek, Josef, Zamecnik, Martin, Kyncl, Zuzana, Holubova, Petr, Liby, Jakub, Taborsky, Vladimir, Benes, Ivana, Pernikova, David, Jones T. W., Martin, Sill, Terezia, Stancokova, Lenka, Krskova, Michal, Zapotocky
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9513869/
https://www.ncbi.nlm.nih.gov/pubmed/36163281
http://dx.doi.org/10.1186/s40478-022-01446-0