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Circulating serum metabolites as predictors of dementia: a machine learning approach in a 21-year follow-up of the Whitehall II cohort study
BACKGROUND: Age is the strongest risk factor for dementia and there is considerable interest in identifying scalable, blood-based biomarkers in predicting dementia. We examined the role of midlife serum metabolites using a machine learning approach and determined whether the selected metabolites imp...
Autores principales: | Machado-Fragua, Marcos D., Landré, Benjamin, Chen, Mathilde, Fayosse, Aurore, Dugravot, Aline, Kivimaki, Mika, Sabia, Séverine, Singh-Manoux, Archana |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9513883/ https://www.ncbi.nlm.nih.gov/pubmed/36163029 http://dx.doi.org/10.1186/s12916-022-02519-6 |
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