MicroRNA miR-627-5p restrains pulmonary artery smooth muscle cell dysfunction by targeting MAP 2 K4 and PI3K/AKT signaling

BACKGROUND: Chronic obstructive pulmonary disease (COPD) is characterized by pulmonary vascular remodeling, which can be caused by abnormal proliferation and migration of pulmonary artery smooth muscle cells (PASMCs). Several microRNAs were demonstrated to regulate the PASMC dysfunction. Our study i...

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Detalles Bibliográficos
Autores principales: Li, Ting, Tan, Xiaoqin, Huang, Yuexia, Cui, Jun, Chen, Fan, Xiong, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9513949/
https://www.ncbi.nlm.nih.gov/pubmed/36163195
http://dx.doi.org/10.1186/s41021-022-00251-4

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