Polyclonal evolution of Fanconi anemia to MDS and AML revealed at single cell resolution

BACKGROUND: Fanconi anemia (FA) is a rare disease of bone marrow failure. FA patients are prone to develop myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML). However, the molecular clonal evolution of the progression from FA to MDS/AML remains elusive. METHODS: Herein, we performed a c...

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Detalles Bibliográficos
Autores principales: Chang, Lixian, Cui, Zejia, Shi, Deyang, Chu, Yajing, Wang, Bichen, Wan, Yang, Ma, Qiuyi, Zhang, Ranran, Li, Haoyuan, Cheng, Xuelian, Cheng, Tao, Zhu, Xiaofan, Li, Cheng, Yuan, Weiping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9513989/
https://www.ncbi.nlm.nih.gov/pubmed/36167633
http://dx.doi.org/10.1186/s40164-022-00319-5

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