Proteomics of Coagulopathy Following Injury Reveals Limitations of Using Laboratory Assessment to Define Trauma-Induced Coagulopathy to Predict Massive Transfusion

OBJECTIVE: Trauma-induced coagulopathy (TIC) is provoked by multiple mechanisms and is perceived to be one driver of massive transfusions (MT). Single laboratory values using prothrombin time (INR) or thrombelastography (TEG) are used to clinically define this complex process. We used a proteomics a...

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Detalles Bibliográficos
Autores principales: Moore, Hunter B., Neal, Matthew D., Bertolet, Marnie, Joughin, Brian A., Yaffe, Michael B., Barrett, Christopher D., Bird, Molly A., Tracy, Russell P., Moore, Ernest E, Sperry, Jason L., Zuckerbraun, Brian S., Park, Myung S., Cohen, Mitchell J., Wisniewski, Stephen R., Morrissey, James H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health, Inc. 2022
Materias:
Original Study
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9514137/
https://www.ncbi.nlm.nih.gov/pubmed/36177090
http://dx.doi.org/10.1097/AS9.0000000000000167

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