Rapid antigen test for SARS-CoV-2: results of validation and use in real life

Aim: To verify a SARS-CoV-2 rapid antigen test (RAT) compared with PCR. Materials & methods: Validation of RAT included 2295 subjects. Next matching of RAT with the PCR was checked in 13,852 subjects referred to PCR after being positive in RAT. Results: Sensitivity and specificity of RAT were 77...

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Autores principales: Kosnik, Irena Grmek, Dermota, Urska, Golle, Andrej, Cretnik, Tjasa Zohar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Future Medicine Ltd 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9514382/
https://www.ncbi.nlm.nih.gov/pubmed/36186521
http://dx.doi.org/10.2217/fvl-2022-0045
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author Kosnik, Irena Grmek
Dermota, Urska
Golle, Andrej
Cretnik, Tjasa Zohar
author_facet Kosnik, Irena Grmek
Dermota, Urska
Golle, Andrej
Cretnik, Tjasa Zohar
author_sort Kosnik, Irena Grmek
collection PubMed
description Aim: To verify a SARS-CoV-2 rapid antigen test (RAT) compared with PCR. Materials & methods: Validation of RAT included 2295 subjects. Next matching of RAT with the PCR was checked in 13,852 subjects referred to PCR after being positive in RAT. Results: Sensitivity and specificity of RAT were 77.38 and 99.10%, respectively. A 74.60% of RAT positive results were confirmed with PCR. Conclusion: The test met WHO susceptibility criteria in a group of symptomatic subjects. In terms of specificity, it met requirements in all subjects. The concordance of RAT with PCR in real life was in line with our verification data.
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spelling pubmed-95143822022-09-28 Rapid antigen test for SARS-CoV-2: results of validation and use in real life Kosnik, Irena Grmek Dermota, Urska Golle, Andrej Cretnik, Tjasa Zohar Future Virol Research Article Aim: To verify a SARS-CoV-2 rapid antigen test (RAT) compared with PCR. Materials & methods: Validation of RAT included 2295 subjects. Next matching of RAT with the PCR was checked in 13,852 subjects referred to PCR after being positive in RAT. Results: Sensitivity and specificity of RAT were 77.38 and 99.10%, respectively. A 74.60% of RAT positive results were confirmed with PCR. Conclusion: The test met WHO susceptibility criteria in a group of symptomatic subjects. In terms of specificity, it met requirements in all subjects. The concordance of RAT with PCR in real life was in line with our verification data. Future Medicine Ltd 2022-09-26 2022-09 /pmc/articles/PMC9514382/ /pubmed/36186521 http://dx.doi.org/10.2217/fvl-2022-0045 Text en © 2022 Irena Grmek Kosnik https://creativecommons.org/licenses/by-nc-nd/4.0/This work is licensed under the Attribution-NonCommercial-NoDerivatives 4.0 Unported License (https://creativecommons.org/licenses/by-nc-nd/4.0/)
spellingShingle Research Article
Kosnik, Irena Grmek
Dermota, Urska
Golle, Andrej
Cretnik, Tjasa Zohar
Rapid antigen test for SARS-CoV-2: results of validation and use in real life
title Rapid antigen test for SARS-CoV-2: results of validation and use in real life
title_full Rapid antigen test for SARS-CoV-2: results of validation and use in real life
title_fullStr Rapid antigen test for SARS-CoV-2: results of validation and use in real life
title_full_unstemmed Rapid antigen test for SARS-CoV-2: results of validation and use in real life
title_short Rapid antigen test for SARS-CoV-2: results of validation and use in real life
title_sort rapid antigen test for sars-cov-2: results of validation and use in real life
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9514382/
https://www.ncbi.nlm.nih.gov/pubmed/36186521
http://dx.doi.org/10.2217/fvl-2022-0045
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