Assessment of minority frequency pretreatment HIV drug-resistant variants in pregnant women and associations with virologic non-suppression at term

OBJECTIVE: To assess in ART-naïve pregnant women randomized to efavirenz- versus raltegravir-based ART (IMPAACT P1081) whether pretreatment drug resistance (PDR) with minority frequency variants (<20% of individual’s viral quasispecies) affects antiretroviral treatment (ART)-suppression at term....

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Detalles Bibliográficos
Autores principales: Boyce, Ceejay L., Beck, Ingrid A., Styrchak, Sheila M., Hardy, Samantha R., Wallner, Jackson J., Milne, Ross S., Morrison, R. Leavitt, Shapiro, David E., João, Esaú C., Mirochnick, Mark H., Frenkel, Lisa M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9514603/
https://www.ncbi.nlm.nih.gov/pubmed/36166463
http://dx.doi.org/10.1371/journal.pone.0275254

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