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Recovery from spindle checkpoint-mediated arrest requires a novel Dnt1-dependent APC/C activation mechanism

The activated spindle assembly checkpoint (SAC) potently inhibits the anaphase-promoting complex/cyclosome (APC/C) to ensure accurate chromosome segregation at anaphase. Early studies have recognized that the SAC should be silenced within minutes to enable rapid APC/C activation and synchronous segr...

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Detalles Bibliográficos
Autores principales:	Bai, Shuang, Sun, Li, Wang, Xi, Wang, Shuang-min, Luo, Zhou-qing, Wang, Yamei, Jin, Quan-wen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9514617/ https://www.ncbi.nlm.nih.gov/pubmed/36108046 http://dx.doi.org/10.1371/journal.pgen.1010397

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