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Giardia duodenalis: Flavohemoglobin is involved in drug biotransformation and resistance to albendazole
Giardia duodenalis causes giardiasis, a major diarrheal disease in humans worldwide whose treatment relies mainly on metronidazole (MTZ) and albendazole (ABZ). The emergence of ABZ resistance in this parasite has prompted studies to elucidate the molecular mechanisms underlying this phenomenon. G. d...
Autores principales: | Pech-Santiago, Edar O., Argüello-García, Raúl, Vázquez, Citlali, Saavedra, Emma, González-Hernández, Iliana, Jung-Cook, Helgi, Rafferty, Steven P., Ortega-Pierres, M. Guadalupe |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9514659/ https://www.ncbi.nlm.nih.gov/pubmed/36166467 http://dx.doi.org/10.1371/journal.ppat.1010840 |
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