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The role of biodegradable temporizing matrix in the management of a patient with major burns and anorexia nervosa

Severe malnutrition secondary to anorexia nervosa results in deeper burns and significantly impacts wound healing, which represents a major challenge to burn management. The use of acellular dermal matrices, such as biodegradable temporizing matrix (BTM), is a valuable tool to overcome the surgical...

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Detalles Bibliográficos
Autores principales: Tan, Poh, Shah, Rushabh, Hassouna, Tarek, Murphy, Ralph, McNally, Samantha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9514796/
https://www.ncbi.nlm.nih.gov/pubmed/36177380
http://dx.doi.org/10.1093/jscr/rjac410
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author Tan, Poh
Shah, Rushabh
Hassouna, Tarek
Murphy, Ralph
McNally, Samantha
author_facet Tan, Poh
Shah, Rushabh
Hassouna, Tarek
Murphy, Ralph
McNally, Samantha
author_sort Tan, Poh
collection PubMed
description Severe malnutrition secondary to anorexia nervosa results in deeper burns and significantly impacts wound healing, which represents a major challenge to burn management. The use of acellular dermal matrices, such as biodegradable temporizing matrix (BTM), is a valuable tool to overcome the surgical limitations. We describe a case of a 36-year-old female with a background of anorexia nervosa (body mass index of 12.3) presenting with a 30% total burns surface area (TBSA) burn. All of her burns were excised down to fascia due to the absence of subcutaneous fat. Her thin skin and depleted nutritional status significantly impacted reconstructive options. BTM was utilized to create a neodermis and provide adequate time to optimize the nutritional status before autologous skin resurfacing 3 weeks later, which yielded robust coverage with minimal donor site morbidity. Despite initial surgical and nutritional challenges, excellent outcomes were achieved in terms of wound healing, scar contractures and mobility.
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spelling pubmed-95147962022-09-28 The role of biodegradable temporizing matrix in the management of a patient with major burns and anorexia nervosa Tan, Poh Shah, Rushabh Hassouna, Tarek Murphy, Ralph McNally, Samantha J Surg Case Rep Case Report Severe malnutrition secondary to anorexia nervosa results in deeper burns and significantly impacts wound healing, which represents a major challenge to burn management. The use of acellular dermal matrices, such as biodegradable temporizing matrix (BTM), is a valuable tool to overcome the surgical limitations. We describe a case of a 36-year-old female with a background of anorexia nervosa (body mass index of 12.3) presenting with a 30% total burns surface area (TBSA) burn. All of her burns were excised down to fascia due to the absence of subcutaneous fat. Her thin skin and depleted nutritional status significantly impacted reconstructive options. BTM was utilized to create a neodermis and provide adequate time to optimize the nutritional status before autologous skin resurfacing 3 weeks later, which yielded robust coverage with minimal donor site morbidity. Despite initial surgical and nutritional challenges, excellent outcomes were achieved in terms of wound healing, scar contractures and mobility. Oxford University Press 2022-09-27 /pmc/articles/PMC9514796/ /pubmed/36177380 http://dx.doi.org/10.1093/jscr/rjac410 Text en Published by Oxford University Press and JSCR Publishing Ltd. All rights reserved. © The Author(s) 2022. https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (https://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Case Report
Tan, Poh
Shah, Rushabh
Hassouna, Tarek
Murphy, Ralph
McNally, Samantha
The role of biodegradable temporizing matrix in the management of a patient with major burns and anorexia nervosa
title The role of biodegradable temporizing matrix in the management of a patient with major burns and anorexia nervosa
title_full The role of biodegradable temporizing matrix in the management of a patient with major burns and anorexia nervosa
title_fullStr The role of biodegradable temporizing matrix in the management of a patient with major burns and anorexia nervosa
title_full_unstemmed The role of biodegradable temporizing matrix in the management of a patient with major burns and anorexia nervosa
title_short The role of biodegradable temporizing matrix in the management of a patient with major burns and anorexia nervosa
title_sort role of biodegradable temporizing matrix in the management of a patient with major burns and anorexia nervosa
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9514796/
https://www.ncbi.nlm.nih.gov/pubmed/36177380
http://dx.doi.org/10.1093/jscr/rjac410
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