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Antimicrobial activities and phytochemical properties of Blumea balsamifera against pathogenic microorganisms
Medicinal plants have been widely used in healthcare based on traditional knowledge. We investigated the antimicrobial activities and phytochemical contents of a plant known as Blumea balsamifera (B. balsamifera), which Sabah native people have used for health benefits. Methanolic extracts and fract...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Carol Davila University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9514820/ https://www.ncbi.nlm.nih.gov/pubmed/36188644 http://dx.doi.org/10.25122/jml-2021-0296 |
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author | Ismail, Nurul Ain Matawali, Azlinah Kanak, Fadzilah Awang Lee, Ping-Chin How, Siew-Eng Goh, Lucky Poh Wah Gansau, Jualang Azlan |
author_facet | Ismail, Nurul Ain Matawali, Azlinah Kanak, Fadzilah Awang Lee, Ping-Chin How, Siew-Eng Goh, Lucky Poh Wah Gansau, Jualang Azlan |
author_sort | Ismail, Nurul Ain |
collection | PubMed |
description | Medicinal plants have been widely used in healthcare based on traditional knowledge. We investigated the antimicrobial activities and phytochemical contents of a plant known as Blumea balsamifera (B. balsamifera), which Sabah native people have used for health benefits. Methanolic extracts and fractions of the leaves of B. balsamifera were tested for their phytochemical contents and their antimicrobial activities against four Gram-negative and five Gram-positive strains of bacteria. The extracts of B. balsamifera showed antimicrobial activities against three Gram-positive, and one Gram-negative bacteria, with the zone of inhibition ranging from 7.8 mm±0.41 to 10.5 mm±0.71. Fraction CE.F7 exerted the broadest antimicrobial activity towards four Gram-positive or Gram-negative bacteria. The phytochemical constituents identified in the extracts were alkaloid, flavonoid, steroid, and cardiac glycosides. The plant extract demonstrated antimicrobial activities and contained multiple phytochemical constituents. Further investigations into potential antimicrobial agents containing promising fractions would validate the medicinal properties of B. balsamifera used in Sabah. |
format | Online Article Text |
id | pubmed-9514820 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Carol Davila University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-95148202022-10-01 Antimicrobial activities and phytochemical properties of Blumea balsamifera against pathogenic microorganisms Ismail, Nurul Ain Matawali, Azlinah Kanak, Fadzilah Awang Lee, Ping-Chin How, Siew-Eng Goh, Lucky Poh Wah Gansau, Jualang Azlan J Med Life Original Article Medicinal plants have been widely used in healthcare based on traditional knowledge. We investigated the antimicrobial activities and phytochemical contents of a plant known as Blumea balsamifera (B. balsamifera), which Sabah native people have used for health benefits. Methanolic extracts and fractions of the leaves of B. balsamifera were tested for their phytochemical contents and their antimicrobial activities against four Gram-negative and five Gram-positive strains of bacteria. The extracts of B. balsamifera showed antimicrobial activities against three Gram-positive, and one Gram-negative bacteria, with the zone of inhibition ranging from 7.8 mm±0.41 to 10.5 mm±0.71. Fraction CE.F7 exerted the broadest antimicrobial activity towards four Gram-positive or Gram-negative bacteria. The phytochemical constituents identified in the extracts were alkaloid, flavonoid, steroid, and cardiac glycosides. The plant extract demonstrated antimicrobial activities and contained multiple phytochemical constituents. Further investigations into potential antimicrobial agents containing promising fractions would validate the medicinal properties of B. balsamifera used in Sabah. Carol Davila University Press 2022-08 /pmc/articles/PMC9514820/ /pubmed/36188644 http://dx.doi.org/10.25122/jml-2021-0296 Text en ©2022 JOURNAL of MEDICINE and LIFE https://creativecommons.org/licenses/by/3.0/This article is distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0/ (https://creativecommons.org/licenses/by/3.0/) ), which permits unrestricted use and redistribution provided that the original author and source are credited. |
spellingShingle | Original Article Ismail, Nurul Ain Matawali, Azlinah Kanak, Fadzilah Awang Lee, Ping-Chin How, Siew-Eng Goh, Lucky Poh Wah Gansau, Jualang Azlan Antimicrobial activities and phytochemical properties of Blumea balsamifera against pathogenic microorganisms |
title | Antimicrobial activities and phytochemical properties of Blumea balsamifera against pathogenic microorganisms |
title_full | Antimicrobial activities and phytochemical properties of Blumea balsamifera against pathogenic microorganisms |
title_fullStr | Antimicrobial activities and phytochemical properties of Blumea balsamifera against pathogenic microorganisms |
title_full_unstemmed | Antimicrobial activities and phytochemical properties of Blumea balsamifera against pathogenic microorganisms |
title_short | Antimicrobial activities and phytochemical properties of Blumea balsamifera against pathogenic microorganisms |
title_sort | antimicrobial activities and phytochemical properties of blumea balsamifera against pathogenic microorganisms |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9514820/ https://www.ncbi.nlm.nih.gov/pubmed/36188644 http://dx.doi.org/10.25122/jml-2021-0296 |
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