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Antimicrobial activities and phytochemical properties of Blumea balsamifera against pathogenic microorganisms

Medicinal plants have been widely used in healthcare based on traditional knowledge. We investigated the antimicrobial activities and phytochemical contents of a plant known as Blumea balsamifera (B. balsamifera), which Sabah native people have used for health benefits. Methanolic extracts and fract...

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Autores principales: Ismail, Nurul Ain, Matawali, Azlinah, Kanak, Fadzilah Awang, Lee, Ping-Chin, How, Siew-Eng, Goh, Lucky Poh Wah, Gansau, Jualang Azlan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Carol Davila University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9514820/
https://www.ncbi.nlm.nih.gov/pubmed/36188644
http://dx.doi.org/10.25122/jml-2021-0296
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author Ismail, Nurul Ain
Matawali, Azlinah
Kanak, Fadzilah Awang
Lee, Ping-Chin
How, Siew-Eng
Goh, Lucky Poh Wah
Gansau, Jualang Azlan
author_facet Ismail, Nurul Ain
Matawali, Azlinah
Kanak, Fadzilah Awang
Lee, Ping-Chin
How, Siew-Eng
Goh, Lucky Poh Wah
Gansau, Jualang Azlan
author_sort Ismail, Nurul Ain
collection PubMed
description Medicinal plants have been widely used in healthcare based on traditional knowledge. We investigated the antimicrobial activities and phytochemical contents of a plant known as Blumea balsamifera (B. balsamifera), which Sabah native people have used for health benefits. Methanolic extracts and fractions of the leaves of B. balsamifera were tested for their phytochemical contents and their antimicrobial activities against four Gram-negative and five Gram-positive strains of bacteria. The extracts of B. balsamifera showed antimicrobial activities against three Gram-positive, and one Gram-negative bacteria, with the zone of inhibition ranging from 7.8 mm±0.41 to 10.5 mm±0.71. Fraction CE.F7 exerted the broadest antimicrobial activity towards four Gram-positive or Gram-negative bacteria. The phytochemical constituents identified in the extracts were alkaloid, flavonoid, steroid, and cardiac glycosides. The plant extract demonstrated antimicrobial activities and contained multiple phytochemical constituents. Further investigations into potential antimicrobial agents containing promising fractions would validate the medicinal properties of B. balsamifera used in Sabah.
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spelling pubmed-95148202022-10-01 Antimicrobial activities and phytochemical properties of Blumea balsamifera against pathogenic microorganisms Ismail, Nurul Ain Matawali, Azlinah Kanak, Fadzilah Awang Lee, Ping-Chin How, Siew-Eng Goh, Lucky Poh Wah Gansau, Jualang Azlan J Med Life Original Article Medicinal plants have been widely used in healthcare based on traditional knowledge. We investigated the antimicrobial activities and phytochemical contents of a plant known as Blumea balsamifera (B. balsamifera), which Sabah native people have used for health benefits. Methanolic extracts and fractions of the leaves of B. balsamifera were tested for their phytochemical contents and their antimicrobial activities against four Gram-negative and five Gram-positive strains of bacteria. The extracts of B. balsamifera showed antimicrobial activities against three Gram-positive, and one Gram-negative bacteria, with the zone of inhibition ranging from 7.8 mm±0.41 to 10.5 mm±0.71. Fraction CE.F7 exerted the broadest antimicrobial activity towards four Gram-positive or Gram-negative bacteria. The phytochemical constituents identified in the extracts were alkaloid, flavonoid, steroid, and cardiac glycosides. The plant extract demonstrated antimicrobial activities and contained multiple phytochemical constituents. Further investigations into potential antimicrobial agents containing promising fractions would validate the medicinal properties of B. balsamifera used in Sabah. Carol Davila University Press 2022-08 /pmc/articles/PMC9514820/ /pubmed/36188644 http://dx.doi.org/10.25122/jml-2021-0296 Text en ©2022 JOURNAL of MEDICINE and LIFE https://creativecommons.org/licenses/by/3.0/This article is distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0/ (https://creativecommons.org/licenses/by/3.0/) ), which permits unrestricted use and redistribution provided that the original author and source are credited.
spellingShingle Original Article
Ismail, Nurul Ain
Matawali, Azlinah
Kanak, Fadzilah Awang
Lee, Ping-Chin
How, Siew-Eng
Goh, Lucky Poh Wah
Gansau, Jualang Azlan
Antimicrobial activities and phytochemical properties of Blumea balsamifera against pathogenic microorganisms
title Antimicrobial activities and phytochemical properties of Blumea balsamifera against pathogenic microorganisms
title_full Antimicrobial activities and phytochemical properties of Blumea balsamifera against pathogenic microorganisms
title_fullStr Antimicrobial activities and phytochemical properties of Blumea balsamifera against pathogenic microorganisms
title_full_unstemmed Antimicrobial activities and phytochemical properties of Blumea balsamifera against pathogenic microorganisms
title_short Antimicrobial activities and phytochemical properties of Blumea balsamifera against pathogenic microorganisms
title_sort antimicrobial activities and phytochemical properties of blumea balsamifera against pathogenic microorganisms
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9514820/
https://www.ncbi.nlm.nih.gov/pubmed/36188644
http://dx.doi.org/10.25122/jml-2021-0296
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