Induction of Severe Eosinophilic Esophagitis and Multi-Organ Inflammation by Airborne Allergens is Associated with IL-4/IL-13 and CCL11 but Not IgE in Genetic Susceptible Mice

BACKGROUND: Eosinophilic Esophagitis (EoE) is an increasingly common chronic inflammatory disease. The pathological mechanisms underlying EoE are largely unknown. OBJECTIVE: We sought to understand the mechanisms underlying aeroallergen-induced EoE in Sharpin gene deficient (Sharpin-/-) mice that is...

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Detalles Bibliográficos
Autores principales: Maskey, Anish, Srivastava, Kamal, Soffer, Gary, Dunkin, David, Yuan, Qian, Li, Xiu-Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2022
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9514888/
https://www.ncbi.nlm.nih.gov/pubmed/36176352
http://dx.doi.org/10.2147/JIR.S372449

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9514888/
https://www.ncbi.nlm.nih.gov/pubmed/36176352
http://dx.doi.org/10.2147/JIR.S372449

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