SQSTM1/p62 promotes miR-198 loading into extracellular vesicles and its autophagy-related secretion

MicroRNA dysregulation is a hallmark of hepatocellular carcinoma (HCC), leading to tumor growth and metastasis. Previous screening on patient specimens identified miR-198 as the most downregulated miRNA in HCC. Here, we show that miR-198 compensation leads to self-release into extracellular vesicles...

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Detalles Bibliográficos
Autores principales: Yu, Xiaojie, Eischeid-Scholz, Hannah, Meder, Lydia, Kondylis, Vangelis, Büttner, Reinhard, Odenthal, Margarete
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Nature Singapore 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9515045/
https://www.ncbi.nlm.nih.gov/pubmed/36050615
http://dx.doi.org/10.1007/s13577-022-00765-7

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