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The ryanodine receptor mutational characteristics and its indication for cancer prognosis

Ca(2+) signaling is altered substantially in many cancers. The ryanodine receptors (RYRs) are among the key ion channels in Ca(2+) signaling. This study aimed to establish the mutational profile of RYR in cancers and investigate the correlation between RYR alterations and cancer phenotypes. The soma...

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Detalles Bibliográficos
Autores principales: Wang, Fenglin, Yu, Jingbo, Lin, Ping, Sigalas, Charalampos, Zhang, Shibo, Gong, Yuan, Sitsapesan, Rebecca, Song, Lele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9515073/
https://www.ncbi.nlm.nih.gov/pubmed/36167878
http://dx.doi.org/10.1038/s41598-022-19905-y