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Durability of clinical and immunologic responses to extended low-dose interleukin-2 therapy in patients with refractory chronic graft-versus-host disease
Chronic graft-versus-host disease (cGVHD) remains a frequent cause of non-relapse morbidity and mortality after allogeneic hematopoietic stem cell transplantation. In our single center trials of low-dose interleukin-2 (LD IL-2), the immunomodulatory properties of regulatory T cells (Tregs) have been...
Autores principales: | Donato, Veronica, Kim, Haesook T., Stowe, Peter, Reynolds, Carol G., Ritz, Jerome, Koreth, John, Whangbo, Jennifer S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9515381/ https://www.ncbi.nlm.nih.gov/pubmed/36189229 http://dx.doi.org/10.3389/fimmu.2022.954966 |
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