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The AhR ligand phthiocol and vitamin K analogs as Pseudomonas aeruginosa quorum sensing inhibitors

The aryl hydrocarbon receptor (AhR) protein senses microbial-secreted metabolites to trigger the host's innate immune system. The Pseudomonas quinolone signal (PQS) and Mycobacterium tuberculosis (MTb) metabolite phthiocol (Pht) are both ligands of AhR with similar chemical structures. As PQS i...

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Detalles Bibliográficos
Autores principales: Jia, Tianyuan, Liu, Dongjing, Bi, Xianbiao, Li, Menglu, Cai, Zhao, Fu, Jiapeng, Liu, Zhi, Wu, Pengyao, Ke, Xue, Jia, Aiqun, Zhang, Guoliang, Li, Guobao, Yang, Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9515472/
https://www.ncbi.nlm.nih.gov/pubmed/36187967
http://dx.doi.org/10.3389/fmicb.2022.896687

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