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Piezo buffers mechanical stress via modulation of intracellular Ca(2+) handling in the Drosophila heart

Throughout its lifetime the heart is buffeted continuously by dynamic mechanical forces resulting from contraction of the heart muscle itself and fluctuations in haemodynamic load and pressure. These forces are in flux on a beat-by-beat basis, resulting from changes in posture, physical activity or...

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Detalles Bibliográficos
Autores principales: Zechini, Luigi, Camilleri-Brennan, Julian, Walsh, Jonathan, Beaven, Robin, Moran, Oscar, Hartley, Paul S., Diaz, Mary, Denholm, Barry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9515499/
https://www.ncbi.nlm.nih.gov/pubmed/36187790
http://dx.doi.org/10.3389/fphys.2022.1003999