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Piezo buffers mechanical stress via modulation of intracellular Ca(2+) handling in the Drosophila heart
Throughout its lifetime the heart is buffeted continuously by dynamic mechanical forces resulting from contraction of the heart muscle itself and fluctuations in haemodynamic load and pressure. These forces are in flux on a beat-by-beat basis, resulting from changes in posture, physical activity or...
Autores principales: | Zechini, Luigi, Camilleri-Brennan, Julian, Walsh, Jonathan, Beaven, Robin, Moran, Oscar, Hartley, Paul S., Diaz, Mary, Denholm, Barry |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9515499/ https://www.ncbi.nlm.nih.gov/pubmed/36187790 http://dx.doi.org/10.3389/fphys.2022.1003999 |
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