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Neutrophil extracellular traps in fungal infections: A seesaw battle in hosts

Fungal infections are a growing health care challenge. Neutrophils play a key role in defense against fungal infections. There are many effective ways for neutrophils to eliminate fungal invaders, such as phagocytosis, oxidative bursts, and the formation of extracellular traps. This process has rece...

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Detalles Bibliográficos
Autores principales: Zhong, Hua, Lu, Ren-Yi, Wang, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9515532/
https://www.ncbi.nlm.nih.gov/pubmed/36189199
http://dx.doi.org/10.3389/fimmu.2022.977493
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author Zhong, Hua
Lu, Ren-Yi
Wang, Yan
author_facet Zhong, Hua
Lu, Ren-Yi
Wang, Yan
author_sort Zhong, Hua
collection PubMed
description Fungal infections are a growing health care challenge. Neutrophils play a key role in defense against fungal infections. There are many effective ways for neutrophils to eliminate fungal invaders, such as phagocytosis, oxidative bursts, and the formation of extracellular traps. This process has received considerable attention and has made rapid progress since neutrophil extracellular traps (NETs) formation was described. Here, we describe the formation, induction, and function of NETs, as well as fungal strategies against NETs hunting. We highlight the effects of NETs on common fungal pathogens and how these pathogens survive.
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spelling pubmed-95155322022-09-29 Neutrophil extracellular traps in fungal infections: A seesaw battle in hosts Zhong, Hua Lu, Ren-Yi Wang, Yan Front Immunol Immunology Fungal infections are a growing health care challenge. Neutrophils play a key role in defense against fungal infections. There are many effective ways for neutrophils to eliminate fungal invaders, such as phagocytosis, oxidative bursts, and the formation of extracellular traps. This process has received considerable attention and has made rapid progress since neutrophil extracellular traps (NETs) formation was described. Here, we describe the formation, induction, and function of NETs, as well as fungal strategies against NETs hunting. We highlight the effects of NETs on common fungal pathogens and how these pathogens survive. Frontiers Media S.A. 2022-09-14 /pmc/articles/PMC9515532/ /pubmed/36189199 http://dx.doi.org/10.3389/fimmu.2022.977493 Text en Copyright © 2022 Zhong, Lu and Wang https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Immunology
Zhong, Hua
Lu, Ren-Yi
Wang, Yan
Neutrophil extracellular traps in fungal infections: A seesaw battle in hosts
title Neutrophil extracellular traps in fungal infections: A seesaw battle in hosts
title_full Neutrophil extracellular traps in fungal infections: A seesaw battle in hosts
title_fullStr Neutrophil extracellular traps in fungal infections: A seesaw battle in hosts
title_full_unstemmed Neutrophil extracellular traps in fungal infections: A seesaw battle in hosts
title_short Neutrophil extracellular traps in fungal infections: A seesaw battle in hosts
title_sort neutrophil extracellular traps in fungal infections: a seesaw battle in hosts
topic Immunology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9515532/
https://www.ncbi.nlm.nih.gov/pubmed/36189199
http://dx.doi.org/10.3389/fimmu.2022.977493
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