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Neutrophil extracellular traps in fungal infections: A seesaw battle in hosts
Fungal infections are a growing health care challenge. Neutrophils play a key role in defense against fungal infections. There are many effective ways for neutrophils to eliminate fungal invaders, such as phagocytosis, oxidative bursts, and the formation of extracellular traps. This process has rece...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Frontiers Media S.A.
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9515532/ https://www.ncbi.nlm.nih.gov/pubmed/36189199 http://dx.doi.org/10.3389/fimmu.2022.977493 |
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author | Zhong, Hua Lu, Ren-Yi Wang, Yan |
author_facet | Zhong, Hua Lu, Ren-Yi Wang, Yan |
author_sort | Zhong, Hua |
collection | PubMed |
description | Fungal infections are a growing health care challenge. Neutrophils play a key role in defense against fungal infections. There are many effective ways for neutrophils to eliminate fungal invaders, such as phagocytosis, oxidative bursts, and the formation of extracellular traps. This process has received considerable attention and has made rapid progress since neutrophil extracellular traps (NETs) formation was described. Here, we describe the formation, induction, and function of NETs, as well as fungal strategies against NETs hunting. We highlight the effects of NETs on common fungal pathogens and how these pathogens survive. |
format | Online Article Text |
id | pubmed-9515532 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-95155322022-09-29 Neutrophil extracellular traps in fungal infections: A seesaw battle in hosts Zhong, Hua Lu, Ren-Yi Wang, Yan Front Immunol Immunology Fungal infections are a growing health care challenge. Neutrophils play a key role in defense against fungal infections. There are many effective ways for neutrophils to eliminate fungal invaders, such as phagocytosis, oxidative bursts, and the formation of extracellular traps. This process has received considerable attention and has made rapid progress since neutrophil extracellular traps (NETs) formation was described. Here, we describe the formation, induction, and function of NETs, as well as fungal strategies against NETs hunting. We highlight the effects of NETs on common fungal pathogens and how these pathogens survive. Frontiers Media S.A. 2022-09-14 /pmc/articles/PMC9515532/ /pubmed/36189199 http://dx.doi.org/10.3389/fimmu.2022.977493 Text en Copyright © 2022 Zhong, Lu and Wang https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Immunology Zhong, Hua Lu, Ren-Yi Wang, Yan Neutrophil extracellular traps in fungal infections: A seesaw battle in hosts |
title | Neutrophil extracellular traps in fungal infections: A seesaw battle in hosts |
title_full | Neutrophil extracellular traps in fungal infections: A seesaw battle in hosts |
title_fullStr | Neutrophil extracellular traps in fungal infections: A seesaw battle in hosts |
title_full_unstemmed | Neutrophil extracellular traps in fungal infections: A seesaw battle in hosts |
title_short | Neutrophil extracellular traps in fungal infections: A seesaw battle in hosts |
title_sort | neutrophil extracellular traps in fungal infections: a seesaw battle in hosts |
topic | Immunology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9515532/ https://www.ncbi.nlm.nih.gov/pubmed/36189199 http://dx.doi.org/10.3389/fimmu.2022.977493 |
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