EGF Contributes to Hypertrophy of Human Ligamentum Flavum via the TGF-β1/Smad3 Signaling Pathway

Background: The most common spinal disorder in elderly is lumbar spinal canal stenosis (LSCS). Previous studies showed that ligamentum flavum hypertrophy (LFH) with fibrosis as the main pathological change is one of the pathogenic factors leading to LSCS. Epidermal Growth Factor (EGF) is known to ha...

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Detalles Bibliográficos
Autores principales: Yang, Kaifan, Chen, Yanlin, Xiang, Xin, Lin, Yanling, Fei, Chengshuo, Chen, Zesen, Lai, Zhongming, Yu, Yongpeng, Tan, Ruiqian, Dong, Jiale, Zhang, Junxiong, Li, Peng, Wang, Liang, Zhang, Zhongmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9515692/
https://www.ncbi.nlm.nih.gov/pubmed/36185336
http://dx.doi.org/10.7150/ijms.76077

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