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Fluphenazine decanoate‐induced bradycardia: A case report

Sinus tachycardia and orthostatic hypotension have been so far reported among the negative cardiovascular complications of antipsychotic agents. This study aimed to report a case with bradycardia induced by fluphenazine decanoate administration. The patient was a 29‐year‐old man, admitted to the gen...

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Autores principales: Kamali, Mahsa, Zarghami, Mehran, Azizi, Marzieh, Elyasi, Forouzan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9515708/
https://www.ncbi.nlm.nih.gov/pubmed/35373519
http://dx.doi.org/10.1002/npr2.12251
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author Kamali, Mahsa
Zarghami, Mehran
Azizi, Marzieh
Elyasi, Forouzan
author_facet Kamali, Mahsa
Zarghami, Mehran
Azizi, Marzieh
Elyasi, Forouzan
author_sort Kamali, Mahsa
collection PubMed
description Sinus tachycardia and orthostatic hypotension have been so far reported among the negative cardiovascular complications of antipsychotic agents. This study aimed to report a case with bradycardia induced by fluphenazine decanoate administration. The patient was a 29‐year‐old man, admitted to the general teaching hospital in Sari, Iran, with a complaint of abdominal and gastric pain as well as weight loss following 7 months of fasting based on religious delusions. The patient developed bradycardia, 36 hours after fluphenazine decanoate administration. His pulse rate was also 46 beats per min (bpm). The antipsychotic medication was thus held and the patient did not take any drugs. On the 21st day after discontinuing this agent, the pulse rate reached 70 bpm. This case report notifies that much more attention should be paid to all patients before starting fluphenazine decanoate administration, and close cardiac monitoring must be done.
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spelling pubmed-95157082022-10-05 Fluphenazine decanoate‐induced bradycardia: A case report Kamali, Mahsa Zarghami, Mehran Azizi, Marzieh Elyasi, Forouzan Neuropsychopharmacol Rep Case Reports Sinus tachycardia and orthostatic hypotension have been so far reported among the negative cardiovascular complications of antipsychotic agents. This study aimed to report a case with bradycardia induced by fluphenazine decanoate administration. The patient was a 29‐year‐old man, admitted to the general teaching hospital in Sari, Iran, with a complaint of abdominal and gastric pain as well as weight loss following 7 months of fasting based on religious delusions. The patient developed bradycardia, 36 hours after fluphenazine decanoate administration. His pulse rate was also 46 beats per min (bpm). The antipsychotic medication was thus held and the patient did not take any drugs. On the 21st day after discontinuing this agent, the pulse rate reached 70 bpm. This case report notifies that much more attention should be paid to all patients before starting fluphenazine decanoate administration, and close cardiac monitoring must be done. John Wiley and Sons Inc. 2022-04-03 /pmc/articles/PMC9515708/ /pubmed/35373519 http://dx.doi.org/10.1002/npr2.12251 Text en © 2022 The Authors. Neuropsychopharmacology Reports published by John Wiley & Sons Australia, Ltd on behalf of The Japanese Society of Neuropsychopharmacology. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Case Reports
Kamali, Mahsa
Zarghami, Mehran
Azizi, Marzieh
Elyasi, Forouzan
Fluphenazine decanoate‐induced bradycardia: A case report
title Fluphenazine decanoate‐induced bradycardia: A case report
title_full Fluphenazine decanoate‐induced bradycardia: A case report
title_fullStr Fluphenazine decanoate‐induced bradycardia: A case report
title_full_unstemmed Fluphenazine decanoate‐induced bradycardia: A case report
title_short Fluphenazine decanoate‐induced bradycardia: A case report
title_sort fluphenazine decanoate‐induced bradycardia: a case report
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9515708/
https://www.ncbi.nlm.nih.gov/pubmed/35373519
http://dx.doi.org/10.1002/npr2.12251
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