Hexokinase 2 Is a Pivot for Lovastatin-induced Glycolysis-to-Autophagy Reprogramming in Triple-Negative Breast Cancer Cells

Triple-negative breast cancer (TNBC) is the most aggressive subtype of breast cancer with limited therapeutic options available. We have recently demonstrated that lovastatin, a 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase inhibitor, suppresses TNBC cell proliferation and stemness prope...

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Detalles Bibliográficos
Autores principales: Xue, Lian, Wu, Mi, Li, Ying, Chen, Sisi, Wu, Muyao, Zhu, Jianyu, Ding, Siyu, Zhang, Qiuting, Zheng, Chanjuan, He, Guangchun, Fu, Shujun, Li, Guifei, Deng, Xiyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9516013/
https://www.ncbi.nlm.nih.gov/pubmed/36186902
http://dx.doi.org/10.7150/jca.71592

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