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Incidence and risk factors of gestational diabetes mellitus in Goba town, Southeast Ethiopia: a prospective cohort study

OBJECTIVE: Gestational diabetes mellitus (GDM) is becoming a public health concern in low/middle-income countries, and is known to cause severe morbidity and mortality for mothers and newborns. However, evidence reported for the incidence and risk factors of GDM is scant in Ethiopia. We aimed to ass...

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Autores principales: Atlaw, Daniel, Sahiledengle, Biniyam, Assefa, Tesfaye, Negash, Wogene, Tahir, Anwar, Regasa, Tadele, Tekalegn, Yohannes, Mamo, Ayele, Enegeda, Zinash Teferu, Solomon, Damtew, Gezahegn, Habtamu, Bekele, Kebebe, Zenbaba, Demisu, Desta, Fikreab, Tasew, Alelign, Nugusu, Fikadu, Beressa, Girma, Shiferaw, Zerihun, Feleke, Zegeye, Regassa, Zegeye, Duguma, Negesso, Chattu, Vijay Kumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9516079/
https://www.ncbi.nlm.nih.gov/pubmed/36167396
http://dx.doi.org/10.1136/bmjopen-2021-060694
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author Atlaw, Daniel
Sahiledengle, Biniyam
Assefa, Tesfaye
Negash, Wogene
Tahir, Anwar
Regasa, Tadele
Tekalegn, Yohannes
Mamo, Ayele
Enegeda, Zinash Teferu
Solomon, Damtew
Gezahegn, Habtamu
Bekele, Kebebe
Zenbaba, Demisu
Desta, Fikreab
Tasew, Alelign
Nugusu, Fikadu
Beressa, Girma
Shiferaw, Zerihun
Feleke, Zegeye
Regassa, Zegeye
Duguma, Negesso
Chattu, Vijay Kumar
author_facet Atlaw, Daniel
Sahiledengle, Biniyam
Assefa, Tesfaye
Negash, Wogene
Tahir, Anwar
Regasa, Tadele
Tekalegn, Yohannes
Mamo, Ayele
Enegeda, Zinash Teferu
Solomon, Damtew
Gezahegn, Habtamu
Bekele, Kebebe
Zenbaba, Demisu
Desta, Fikreab
Tasew, Alelign
Nugusu, Fikadu
Beressa, Girma
Shiferaw, Zerihun
Feleke, Zegeye
Regassa, Zegeye
Duguma, Negesso
Chattu, Vijay Kumar
author_sort Atlaw, Daniel
collection PubMed
description OBJECTIVE: Gestational diabetes mellitus (GDM) is becoming a public health concern in low/middle-income countries, and is known to cause severe morbidity and mortality for mothers and newborns. However, evidence reported for the incidence and risk factors of GDM is scant in Ethiopia. We aimed to assess the incidence of, and risk factors for, GDM in Goba town, Southeast Ethiopia. DESIGN: Prospective cohort study. SETTING: Goba town, Southeast Ethiopia. PARTICIPANTS: Four hundred eighty pregnant women on antenatal care follow-up from 30 April to 30 September 2021. PRIMARY AND SECONDARY OUTCOMES: Incidence and risk factors of GDM using fasting capillary blood glucose. Log-binomial model was used to identify the risk factors of GDM. Adjusted relative risk (aRR), along with 95% CIs, were calculated to estimate the strength of associations. RESULTS: The cumulative incidence rate of GDM in this study was 15.7% (95% CI: 12.3% to 19.2%). Being unemployed (aRR=2.73; 95% CI: 1.36 to 5.47), having a family history of diabetes mellitus (DM) (3.01; 2.09 to 4.35), low physical activity (2.43; 1.11 to 5.32), inadequate dietary diversity (1.48; 1.29 to 1.92), anaemia (2.51; 1.32 to 3.54) and antenatal depression (4.95; 3.35 to 7.31) were significantly associated with GDM. CONCLUSION: The cumulative incidence of GDM was relatively high among the study participants. Having antenatal depression symptoms, low physical activity, inadequate dietary diversity, being unemployed, anaemia and a family history of DM were significant risk factors for GDM.
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spelling pubmed-95160792022-09-29 Incidence and risk factors of gestational diabetes mellitus in Goba town, Southeast Ethiopia: a prospective cohort study Atlaw, Daniel Sahiledengle, Biniyam Assefa, Tesfaye Negash, Wogene Tahir, Anwar Regasa, Tadele Tekalegn, Yohannes Mamo, Ayele Enegeda, Zinash Teferu Solomon, Damtew Gezahegn, Habtamu Bekele, Kebebe Zenbaba, Demisu Desta, Fikreab Tasew, Alelign Nugusu, Fikadu Beressa, Girma Shiferaw, Zerihun Feleke, Zegeye Regassa, Zegeye Duguma, Negesso Chattu, Vijay Kumar BMJ Open Diabetes and Endocrinology OBJECTIVE: Gestational diabetes mellitus (GDM) is becoming a public health concern in low/middle-income countries, and is known to cause severe morbidity and mortality for mothers and newborns. However, evidence reported for the incidence and risk factors of GDM is scant in Ethiopia. We aimed to assess the incidence of, and risk factors for, GDM in Goba town, Southeast Ethiopia. DESIGN: Prospective cohort study. SETTING: Goba town, Southeast Ethiopia. PARTICIPANTS: Four hundred eighty pregnant women on antenatal care follow-up from 30 April to 30 September 2021. PRIMARY AND SECONDARY OUTCOMES: Incidence and risk factors of GDM using fasting capillary blood glucose. Log-binomial model was used to identify the risk factors of GDM. Adjusted relative risk (aRR), along with 95% CIs, were calculated to estimate the strength of associations. RESULTS: The cumulative incidence rate of GDM in this study was 15.7% (95% CI: 12.3% to 19.2%). Being unemployed (aRR=2.73; 95% CI: 1.36 to 5.47), having a family history of diabetes mellitus (DM) (3.01; 2.09 to 4.35), low physical activity (2.43; 1.11 to 5.32), inadequate dietary diversity (1.48; 1.29 to 1.92), anaemia (2.51; 1.32 to 3.54) and antenatal depression (4.95; 3.35 to 7.31) were significantly associated with GDM. CONCLUSION: The cumulative incidence of GDM was relatively high among the study participants. Having antenatal depression symptoms, low physical activity, inadequate dietary diversity, being unemployed, anaemia and a family history of DM were significant risk factors for GDM. BMJ Publishing Group 2022-09-26 /pmc/articles/PMC9516079/ /pubmed/36167396 http://dx.doi.org/10.1136/bmjopen-2021-060694 Text en © Author(s) (or their employer(s)) 2022. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. https://creativecommons.org/licenses/by-nc/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) .
spellingShingle Diabetes and Endocrinology
Atlaw, Daniel
Sahiledengle, Biniyam
Assefa, Tesfaye
Negash, Wogene
Tahir, Anwar
Regasa, Tadele
Tekalegn, Yohannes
Mamo, Ayele
Enegeda, Zinash Teferu
Solomon, Damtew
Gezahegn, Habtamu
Bekele, Kebebe
Zenbaba, Demisu
Desta, Fikreab
Tasew, Alelign
Nugusu, Fikadu
Beressa, Girma
Shiferaw, Zerihun
Feleke, Zegeye
Regassa, Zegeye
Duguma, Negesso
Chattu, Vijay Kumar
Incidence and risk factors of gestational diabetes mellitus in Goba town, Southeast Ethiopia: a prospective cohort study
title Incidence and risk factors of gestational diabetes mellitus in Goba town, Southeast Ethiopia: a prospective cohort study
title_full Incidence and risk factors of gestational diabetes mellitus in Goba town, Southeast Ethiopia: a prospective cohort study
title_fullStr Incidence and risk factors of gestational diabetes mellitus in Goba town, Southeast Ethiopia: a prospective cohort study
title_full_unstemmed Incidence and risk factors of gestational diabetes mellitus in Goba town, Southeast Ethiopia: a prospective cohort study
title_short Incidence and risk factors of gestational diabetes mellitus in Goba town, Southeast Ethiopia: a prospective cohort study
title_sort incidence and risk factors of gestational diabetes mellitus in goba town, southeast ethiopia: a prospective cohort study
topic Diabetes and Endocrinology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9516079/
https://www.ncbi.nlm.nih.gov/pubmed/36167396
http://dx.doi.org/10.1136/bmjopen-2021-060694
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