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Incidence and risk factors of gestational diabetes mellitus in Goba town, Southeast Ethiopia: a prospective cohort study
OBJECTIVE: Gestational diabetes mellitus (GDM) is becoming a public health concern in low/middle-income countries, and is known to cause severe morbidity and mortality for mothers and newborns. However, evidence reported for the incidence and risk factors of GDM is scant in Ethiopia. We aimed to ass...
Autores principales: | , , , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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BMJ Publishing Group
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9516079/ https://www.ncbi.nlm.nih.gov/pubmed/36167396 http://dx.doi.org/10.1136/bmjopen-2021-060694 |
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author | Atlaw, Daniel Sahiledengle, Biniyam Assefa, Tesfaye Negash, Wogene Tahir, Anwar Regasa, Tadele Tekalegn, Yohannes Mamo, Ayele Enegeda, Zinash Teferu Solomon, Damtew Gezahegn, Habtamu Bekele, Kebebe Zenbaba, Demisu Desta, Fikreab Tasew, Alelign Nugusu, Fikadu Beressa, Girma Shiferaw, Zerihun Feleke, Zegeye Regassa, Zegeye Duguma, Negesso Chattu, Vijay Kumar |
author_facet | Atlaw, Daniel Sahiledengle, Biniyam Assefa, Tesfaye Negash, Wogene Tahir, Anwar Regasa, Tadele Tekalegn, Yohannes Mamo, Ayele Enegeda, Zinash Teferu Solomon, Damtew Gezahegn, Habtamu Bekele, Kebebe Zenbaba, Demisu Desta, Fikreab Tasew, Alelign Nugusu, Fikadu Beressa, Girma Shiferaw, Zerihun Feleke, Zegeye Regassa, Zegeye Duguma, Negesso Chattu, Vijay Kumar |
author_sort | Atlaw, Daniel |
collection | PubMed |
description | OBJECTIVE: Gestational diabetes mellitus (GDM) is becoming a public health concern in low/middle-income countries, and is known to cause severe morbidity and mortality for mothers and newborns. However, evidence reported for the incidence and risk factors of GDM is scant in Ethiopia. We aimed to assess the incidence of, and risk factors for, GDM in Goba town, Southeast Ethiopia. DESIGN: Prospective cohort study. SETTING: Goba town, Southeast Ethiopia. PARTICIPANTS: Four hundred eighty pregnant women on antenatal care follow-up from 30 April to 30 September 2021. PRIMARY AND SECONDARY OUTCOMES: Incidence and risk factors of GDM using fasting capillary blood glucose. Log-binomial model was used to identify the risk factors of GDM. Adjusted relative risk (aRR), along with 95% CIs, were calculated to estimate the strength of associations. RESULTS: The cumulative incidence rate of GDM in this study was 15.7% (95% CI: 12.3% to 19.2%). Being unemployed (aRR=2.73; 95% CI: 1.36 to 5.47), having a family history of diabetes mellitus (DM) (3.01; 2.09 to 4.35), low physical activity (2.43; 1.11 to 5.32), inadequate dietary diversity (1.48; 1.29 to 1.92), anaemia (2.51; 1.32 to 3.54) and antenatal depression (4.95; 3.35 to 7.31) were significantly associated with GDM. CONCLUSION: The cumulative incidence of GDM was relatively high among the study participants. Having antenatal depression symptoms, low physical activity, inadequate dietary diversity, being unemployed, anaemia and a family history of DM were significant risk factors for GDM. |
format | Online Article Text |
id | pubmed-9516079 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | BMJ Publishing Group |
record_format | MEDLINE/PubMed |
spelling | pubmed-95160792022-09-29 Incidence and risk factors of gestational diabetes mellitus in Goba town, Southeast Ethiopia: a prospective cohort study Atlaw, Daniel Sahiledengle, Biniyam Assefa, Tesfaye Negash, Wogene Tahir, Anwar Regasa, Tadele Tekalegn, Yohannes Mamo, Ayele Enegeda, Zinash Teferu Solomon, Damtew Gezahegn, Habtamu Bekele, Kebebe Zenbaba, Demisu Desta, Fikreab Tasew, Alelign Nugusu, Fikadu Beressa, Girma Shiferaw, Zerihun Feleke, Zegeye Regassa, Zegeye Duguma, Negesso Chattu, Vijay Kumar BMJ Open Diabetes and Endocrinology OBJECTIVE: Gestational diabetes mellitus (GDM) is becoming a public health concern in low/middle-income countries, and is known to cause severe morbidity and mortality for mothers and newborns. However, evidence reported for the incidence and risk factors of GDM is scant in Ethiopia. We aimed to assess the incidence of, and risk factors for, GDM in Goba town, Southeast Ethiopia. DESIGN: Prospective cohort study. SETTING: Goba town, Southeast Ethiopia. PARTICIPANTS: Four hundred eighty pregnant women on antenatal care follow-up from 30 April to 30 September 2021. PRIMARY AND SECONDARY OUTCOMES: Incidence and risk factors of GDM using fasting capillary blood glucose. Log-binomial model was used to identify the risk factors of GDM. Adjusted relative risk (aRR), along with 95% CIs, were calculated to estimate the strength of associations. RESULTS: The cumulative incidence rate of GDM in this study was 15.7% (95% CI: 12.3% to 19.2%). Being unemployed (aRR=2.73; 95% CI: 1.36 to 5.47), having a family history of diabetes mellitus (DM) (3.01; 2.09 to 4.35), low physical activity (2.43; 1.11 to 5.32), inadequate dietary diversity (1.48; 1.29 to 1.92), anaemia (2.51; 1.32 to 3.54) and antenatal depression (4.95; 3.35 to 7.31) were significantly associated with GDM. CONCLUSION: The cumulative incidence of GDM was relatively high among the study participants. Having antenatal depression symptoms, low physical activity, inadequate dietary diversity, being unemployed, anaemia and a family history of DM were significant risk factors for GDM. BMJ Publishing Group 2022-09-26 /pmc/articles/PMC9516079/ /pubmed/36167396 http://dx.doi.org/10.1136/bmjopen-2021-060694 Text en © Author(s) (or their employer(s)) 2022. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. https://creativecommons.org/licenses/by-nc/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) . |
spellingShingle | Diabetes and Endocrinology Atlaw, Daniel Sahiledengle, Biniyam Assefa, Tesfaye Negash, Wogene Tahir, Anwar Regasa, Tadele Tekalegn, Yohannes Mamo, Ayele Enegeda, Zinash Teferu Solomon, Damtew Gezahegn, Habtamu Bekele, Kebebe Zenbaba, Demisu Desta, Fikreab Tasew, Alelign Nugusu, Fikadu Beressa, Girma Shiferaw, Zerihun Feleke, Zegeye Regassa, Zegeye Duguma, Negesso Chattu, Vijay Kumar Incidence and risk factors of gestational diabetes mellitus in Goba town, Southeast Ethiopia: a prospective cohort study |
title | Incidence and risk factors of gestational diabetes mellitus in Goba town, Southeast Ethiopia: a prospective cohort study |
title_full | Incidence and risk factors of gestational diabetes mellitus in Goba town, Southeast Ethiopia: a prospective cohort study |
title_fullStr | Incidence and risk factors of gestational diabetes mellitus in Goba town, Southeast Ethiopia: a prospective cohort study |
title_full_unstemmed | Incidence and risk factors of gestational diabetes mellitus in Goba town, Southeast Ethiopia: a prospective cohort study |
title_short | Incidence and risk factors of gestational diabetes mellitus in Goba town, Southeast Ethiopia: a prospective cohort study |
title_sort | incidence and risk factors of gestational diabetes mellitus in goba town, southeast ethiopia: a prospective cohort study |
topic | Diabetes and Endocrinology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9516079/ https://www.ncbi.nlm.nih.gov/pubmed/36167396 http://dx.doi.org/10.1136/bmjopen-2021-060694 |
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