MCM6 is a critical transcriptional target of YAP to promote gastric tumorigenesis and serves as a therapeutic target

Rationale: Hyperactivation of Hippo-Yes-associated protein (YAP) signaling pathway governs tumorigenesis of gastric cancer (GC). Here we reveal that minichromosome maintenance complex component 6 (MCM6) is a critical transcriptional target of YAP in GC. We aim to investigate the function, mechanism...

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Detalles Bibliográficos
Autores principales: Wang, Yifei, Chen, Huarong, Liu, Weixin, Yan, Huan, Zhang, Yihan, Cheung, Alvin H.K., Zhang, Jinglin, Chen, Bonan, Liang, Li, Zhou, Zhaocai, Wong, Chi Chun, Wu, William K.K., Chan, Michael W.Y., Cheng, Alfred S.L., Ma, Brigette B.Y., Yu, Jun, Lo, Kwok Wai, To, Ka Fai, Kang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9516235/
https://www.ncbi.nlm.nih.gov/pubmed/36185598
http://dx.doi.org/10.7150/thno.75431

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