Cargando…

Saikosaponin D improves chemosensitivity of glioblastoma by reducing the its stemness maintenance

OBJECTIVE: Chemotherapy is one of the important adjuvant methods for the treatment of glioblastoma (GBM), and chemotherapy resistance is a clinical problem that neurooncologists need to solve urgently. It is reported that Saikosaponin D (SSD), an active component of Bupleurum chinense, had various o...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liang, Jin, Sun, Jing, Liu, Aibin, Chen, Lei, Ma, Xiaofang, Liu, Xiaozhi, Zhang, Chunyan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9516410/ https://www.ncbi.nlm.nih.gov/pubmed/36186734 http://dx.doi.org/10.1016/j.bbrep.2022.101342

Ejemplares similares

Dexamethasone inhibits stemness maintenance and enhances chemosensitivity of hepatocellular carcinoma stem cells by inducing deSUMOylation of HIF-1α and Oct4
por: Jiang, Zhongmin, et al.
Publicado: (2020)

Saikosaponin D Inducing Apoptosis and Autophagy through the Activation of Endoplasmic Reticulum Stress in Glioblastoma
por: Liu, Guimei, et al.
Publicado: (2022)

Formulations, Hemolytic and Pharmacokinetic Studies on Saikosaponin a and Saikosaponin d Compound Liposomes
por: Zhang, Guo-Song, et al.
Publicado: (2015)

Saikosaponin-d Inhibits the Hepatoma Cells and Enhances Chemosensitivity Through SENP5-Dependent Inhibition of Gli1 SUMOylation Under Hypoxia
por: Zhang, Chun-Yan, et al.
Publicado: (2019)

MicroRNA 145 enhances chemosensitivity of glioblastoma stem cells to demethoxycurcumin
por: Qian, Chunfa, et al.
Publicado: (2019)

Reactive oxygen species-mediated apoptosis contributes to chemosensitization effect of saikosaponins on cisplatin-induced cytotoxicity in cancer cells
por: Wang, Qiong, et al.
Publicado: (2010)

Saikosaponin D: review on the antitumour effects, toxicity and pharmacokinetics
por: Zhou, Piao, et al.
Publicado: (2021)

Chemotherapeutic Potential of Saikosaponin D: Experimental Evidence
por: Manoharan, Suryaa, et al.
Publicado: (2022)

Facile Synthesis of Saikosaponins
por: Wang, Ziqiang, et al.
Publicado: (2021)

Saikosaponin-d Attenuates Hashimoto's Thyroiditis by Regulating Macrophage Polarization
por: Du, Peng, et al.
Publicado: (2022)

Interaction between Saikosaponin D, Paeoniflorin, and Human Serum Albumin
por: Liang, Guo-Wu, et al.
Publicado: (2018)

Saikosaponin D suppresses enterovirus A71 infection by inhibiting autophagy
por: Li, Chang, et al.
Publicado: (2019)

Saikosaponin D reverses epinephrine- and norepinephrine-induced gemcitabine resistance in intrahepatic cholangiocarcinoma by downregulating ADRB2/glycolysis signaling: Saikosaponin D reverses gemcitabine resistance
por: He, Hui, et al.
Publicado: (2023)

Saikosaponin A and Saikosaponin C Reduce TNF-α-Induced TSLP Expression through Inhibition of MAPK-Mediated EGR1 Expression in HaCaT Keratinocytes
por: Ahn, Sung Shin, et al.
Publicado: (2022)

Purposing Saikosaponins for the treatment of COVID-19
por: Bahbah, Eshak I., et al.
Publicado: (2020)

Effects and Mechanisms of Saikosaponin D Improving the Sensitivity of Human Gastric Cancer Cells to Cisplatin
por: Hu, Jianran, et al.
Publicado: (2021)

Metabolomics Reveals the Efficacy of Caspase Inhibition for Saikosaponin D-Induced Hepatotoxicity
por: Zhang, Qian-qian, et al.
Publicado: (2018)

Immunocytochemical localization of saikosaponin-d in vegetative organs of Bupleurum scorzonerifolium Willd
por: Zhao, Xueyan, et al.
Publicado: (2013)

Saikosaponin-d Increases the Radiosensitivity of Hepatoma Cells by Adjusting Cell Autophagy
por: Tian, Yin-Di, et al.
Publicado: (2019)

Screening saikosaponin d (SSd)-producing endophytic fungi from Bupleurum scorzonerifolium Willd
por: Cheng, Yupeng, et al.
Publicado: (2022)

Reparative and toxicity-reducing effects of liposome-encapsulated saikosaponin in mice with liver fibrosis
por: Shiu, Li-Yen, et al.
Publicado: (2020)

Dynamics of chemosensitivity and chromosomal instability in recurrent glioblastoma
por: Spiegl-Kreinecker, S, et al.
Publicado: (2007)

A comprehensive review and perspectives on pharmacology and toxicology of saikosaponins
por: Li, Xiaojiaoyang, et al.
Publicado: (2018)

Cognitive improvements and reduction in amyloid plaque deposition by saikosaponin D treatment in a murine model of Alzheimer's disease
por: Zhou, Li, et al.
Publicado: (2020)

Saikosaponin-d affects the differentiation, maturation and function of monocyte-derived dendritic cells
por: YING, ZUO-LIN, et al.
Publicado: (2014)

Investigation on ultrasound assisted extraction of saikosaponins from Radix Bupleuri
por: Zhao, Shuna, et al.
Publicado: (2007)

Targeting RAD51 enhances chemosensitivity of adult T-cell leukemia-lymphoma cells by reducing DNA double-strand break repair
por: Yang, Meng, et al.
Publicado: (2019)

The potential effect and mechanism of Saikosaponin A against gastric cancer
por: Wang, Chao, et al.
Publicado: (2023)

Smurf1 Suppression Enhances Temozolomide Chemosensitivity in Glioblastoma by Facilitating PTEN Nuclear Translocation
por: Dong, Lei, et al.
Publicado: (2022)

Saikosaponins A, C and D enhance liver-targeting effects of anticancer drugs by modulating drug transporters
por: Feng, Limin, et al.
Publicado: (2017)

Saikosaponin D Inhibits the Proliferation and Promotes the Apoptosis of Rat Hepatic Stellate Cells by Inducing Autophagosome Formation
por: Jiang, Hong, et al.
Publicado: (2021)

Mechanism of the effect of saikosaponin on atherosclerosis in vitro is based on the MAPK signaling pathway
por: Yang, Lin, et al.
Publicado: (2017)

A Highly Sensitive Immunochromatographic Strip Test for Rapid and Quantitative Detection of Saikosaponin d
por: Zhang, Yue, et al.
Publicado: (2018)

Saikosaponin D Isolated from Bupleurum falcatum Inhibits Selectin-Mediated Cell Adhesion
por: Jang, Myoung-Jun, et al.
Publicado: (2014)

Saikosaponin-d alleviates hepatic fibrosis through regulating GPER1/autophagy signaling
por: Chen, Yirong, et al.
Publicado: (2021)

Untargeted Metabolomics Study of the In Vitro Anti-Hepatoma Effect of Saikosaponin d in Combination with NRP-1 Knockdown
por: Lv, Yingtong, et al.
Publicado: (2019)

Ivacaftor Inhibits Glioblastoma Stem Cell Maintenance and Tumor Progression
por: Liu, Kun, et al.
Publicado: (2021)

Saikosaponin A and Its Epimers Alleviate LPS-Induced Acute Lung Injury in Mice
por: Peng, Donghui, et al.
Publicado: (2023)

Saikosaponin-d Enhances the Anticancer Potency of TNF-α via Overcoming Its Undesirable Response of Activating NF-Kappa B Signalling in Cancer Cells
por: Wong, Vincent Kam Wai, et al.
Publicado: (2013)

Putative Genes Involved in Saikosaponin Biosynthesis in Bupleurum Species
por: Lin, Tsai-Yun, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_gskcdnbcc88to0p9tirecrg398